A study on contagious viruses based on mortality of statistical data of pandemic

Sathiyaraj, G.; Vaithyasubramanian, S.

doi:10.1063/5.0108403

Cited by 1 publication

(2 citation statements)

References 21 publications

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“…Viruses can generate several diseases such as: acquired immunodeficiency syndrome, dengue, Middle East respiratory syndrome, polio, etc. [ 3 , 4 ]. Viruses infect healthy cells and cause apoptosis in infected cells.…”

Section: An Introduction To Thymoquinone and Viral Diseasesmentioning

confidence: 99%

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Cellular, Molecular, Pharmacological, and Nano-Formulation Aspects of Thymoquinone—A Potent Natural Antiviral Agent

et al. 2023

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The goal of an antiviral agent research is to find an antiviral drug that reduces viral growth without harming healthy cells. Transformations of the virus, new viral strain developments, the resistance of viral pathogens, and side effects are the current challenges in terms of discovering antiviral drugs. The time has come and it is now essential to discover a natural antiviral agent that has the potential to destroy viruses without causing resistance or other unintended side effects. The pharmacological potency of thymoquinone (TQ) against different communicable and non-communicable diseases has been proven by various studies, and TQ is considered to be a safe antiviral substitute. Adjunctive immunomodulatory effects in addition to the antiviral potency of TQ makes it a major compound against viral infection through modulating the production of nitric oxide and reactive oxygen species, decreasing the cytokine storm, and inhibiting endothelial dysfunction. Nevertheless, TQ’s low oral bioavailability, short half-life, poor water solubility, and conventional formulation are barriers to achieving its optimal pharmacologic benefits. Nano-formulation proposes numerous ways to overcome these obstacles through a small particle size, a big surface area, and a variety of surface modifications. Nano-based pharmaceutical innovations to combat viral infections using TQ are a promising approach to treating surmounting viral infections.

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Section: An Introduction To Thymoquinone and Viral Diseasesmentioning

confidence: 99%

“…Viruses can generate several diseases such as: acquired immunodeficiency syndrome, dengue, Middle East respiratory syndrome, polio, etc. [3,4].…”

Section: An Introduction To Thymoquinone and Viral Diseasesmentioning

confidence: 99%

Cellular, Molecular, Pharmacological, and Nano-Formulation Aspects of Thymoquinone—A Potent Natural Antiviral Agent

et al. 2023

View full text Add to dashboard Cite

show abstract

A study on contagious viruses based on mortality of statistical data of pandemic

Cited by 1 publication

References 21 publications

Cellular, Molecular, Pharmacological, and Nano-Formulation Aspects of Thymoquinone—A Potent Natural Antiviral Agent

Cellular, Molecular, Pharmacological, and Nano-Formulation Aspects of Thymoquinone—A Potent Natural Antiviral Agent

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