A study on median nerve conduction velocity in different age groups

Senthilkumari, K. R.; Umamaheswari, K.; Bhaskaran, Mythili

doi:10.18203/2320-6012.ijrms20151183

Cited by 6 publications

(5 citation statements)

References 6 publications

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“…Further, the deterioration of the myelin sheath and axonal atrophy during aging affects the electrophysiologic properties of the peripheral nerves. [ 25 , 26 ] Consistent with this knowledge, in our study, age correlated with the abnormalities in the electrophysiologic properties of the nerves in the lower extremities.…”

Section: Discussionsupporting

confidence: 89%

Can the severity of central lumbar stenosis affect the results of nerve conduction study?

Jang

Lee²

2020

Medicine

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To evaluate the effect of the severity of spinal stenosis on the peripheral nerves of lower extremities by nerve conduction study (NCS). One hundred fifteen patients with lumbar spinal stenosis were recruited retrospectively in this study. The grading system for lumbar stenosis was used based on the degree of separation of the cauda equina. The degree of cauda equina damage caused by lumbar central stenosis was assessed by NCS of peripheral nerves. Multiple regression analysis was used to estimate which factors affect peripheral nerve injury, according to the presence of DM, total grading of lumbar central stenosis, and age. Only age was associated with low amplitude in the tibial and peroneal motor NCS in the multiple regression analysis. The severity of the compression of the cauda equina, caused by spinal stenosis, did not statistically significantly affect the NCS values of nerves on the lower extremities. In conclusion, the cauda equina is resilient against degenerative lumbar central stenosis. Unlike changes caused by peripheral nerve entrapment, lumbar central stenosis did not affect the findings of NCS on the peripheral nerve of lower extremities.

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Section: Discussionsupporting

confidence: 89%

Can the severity of central lumbar stenosis affect the results of nerve conduction study?

Jang

Lee²

2020

Medicine

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“…It is essential to have reference values with relation to age. [ 16 ] Age has definite effects on the duration of motor and sensory nerves; different nerves have different timing of aging. Without adjustment for age, the sensitivity and specificity of NCS will decrease when using the same reference data in patients with different age.…”

Section: Discussionmentioning

confidence: 99%

“…Without adjustment for age, the sensitivity and specificity of NCS will decrease when using the same reference data in patients with different age. [ 5 6 16 ] The age factor was negatively correlated to the amplitude in both motor and sensory NCSs and velocity in motor NCS. [ 15 ] The F-wave and H-reflex were positively correlated to age and height, but negatively correlated to velocity[ 14 15 ] and the same is proved in our study, we enrolled the data from persons without symptoms and signs of any neurological disorder.…”

Section: Discussionmentioning

confidence: 99%

Impact of Aging on Nerve Conduction Velocities and Late Responses in Healthy Individuals

Palve

2018

Journal of Neurosciences in Rural Practice

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Background:Nerve conduction studies are performed to diagnose the disorders of the peripheral nervous system. The reference values for nerve conduction velocity (NCV) and late responses for different nerves considerably vary in different group and type of population. Physiological factors such as age, temperature, height, and gender affect the NCV. However, there are very few studies which show the age group at which these changes become significant.Aim and Objectives:The aim of the study was to establish the electrophysiological data of the specific age group at which changes in NCV as well as late responses of median common peroneal nerve and also see the late response in the form of F-waves and H-reflex.Methodology:Study groups were divided into three categories based on the age: Group I (18–30 years) (n = 80), Group II (31–45 years) (n = 43), and Group III (46–60 years) (n = 27). Out of which, 93 patients were male and 57 were female. The NCVs were determined for median, common peroneal nerve (motor component and sensory component) along with late responses in the form of H-reflex and F-waves.Results:The mean and standard deviation of median, ulnar, peroneal, and tibial nerve was studied for latencies, amplitude, and velocities for both sensory and motor components. Patients with older age had longer latencies, smaller amplitudes, and slower conduction velocities compared with the younger age group. The change with age was greater in sensory nerve conduction and late responses in all the peripheral nerves.Conclusions:Aging has a definite correlation with the NCV and late responses of different peripheral nerves. There is a need to have reference values with relation to age.

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“…NCV relies on age, temperature, height, gender, nerve fiber diameter, myelination and inter nodal distance. [18][19] Demyelinating neuropathy usually shows slowing of NCV. [20] Results of nerve conduction amplitude in the studied groups…”

Section: Biochemical Analysismentioning

confidence: 99%

The Relationship between Dyslipidemia, Antioxidants and Nerve Conduction Velocity in Overweight and Obese Persons in Aswan

Elsaied

Sedeek

Fehr

et al. 2019

IJCEP

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Background and Aim: Overweight and obesity are major health problems leading to peripheral neuropathy. The exact mechanism of peripheral neuropathy in obesity is uncertain. However, increased oxidative stress and dyslipidemia are potential pathways. To find out the relationship between obesity and peripheral neuropathy in adults in Upper Egypt. Also, to clarify the role of dyslipidemia and oxidative stress in obesity-related neuropathy. Methods: Study groups are: normal weight, overweight and obese group (25 subjects in each group). All individuals underwent nerve conduction studies (NCS) of both median and ulnar nerves. In addition, lipid profile, TAC and MDA were measured in the serum. Result: We found significant increase in LDL, TG and MDA and significant reduction in HDL in obese compared to normal weight subjects. NCS showed significant slowing of NCV of right median motor and left median sensory, decrease in amplitude of ulnar motor nerves on both sides and right median motor nerve. Overweight group showed significant increase in LDL, TC and MDA compared to normal weight group. Conclusion: Our study suggested that obesity induces peripheral neuropathy. It also suggested that oxidative stress and dyslipidemia play an important role in the pathogenesis of obesity-related neuropathy.

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A study on median nerve conduction velocity in different age groups

Cited by 6 publications

References 6 publications

Can the severity of central lumbar stenosis affect the results of nerve conduction study?

Can the severity of central lumbar stenosis affect the results of nerve conduction study?

Impact of Aging on Nerve Conduction Velocities and Late Responses in Healthy Individuals

The Relationship between Dyslipidemia, Antioxidants and Nerve Conduction Velocity in Overweight and Obese Persons in Aswan

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