A study on Newcastle disease virus pathotypes in Zambia

Hussein, N A; Sharma, Rakesh; Ando, Ryosuke; Chizyuka, H. G. B.

doi:10.20506/rst.3.2.159

Cited by 3 publications

(2 citation statements)

References 1 publication

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“…Similarly, a vaccination programme amongst village and backyard chickens would limit mortalities, improve flock numbers and ultimately improve food security and generate much-needed income for many poor households in the country. Since the last study to isolate and characterise ND strains responsible for losses in the Zambian poultry sector was published almost 30 years ago (Hussein et al 1984), there is a need to isolate and genetically characterise currently circulating strains affecting poultry in Zambia to allow appropriate control decisions to be taken.…”

Section: Discussionmentioning

confidence: 99%

Determination of the seroprevalence of Newcastle disease virus (avian paramyxovirus type 1) in Zambian backyard chicken flocks

Musako

Abolnik

2012

Onderstepoort J Vet Res

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A cross-sectional study was conducted in five provinces and 11 districts of Zambia to determine the seroprevalence of Newcastle disease in Zambian backyard chicken flocks. Of the chickens sampled, 73.9% tested positive for avian paramyxovirus type 1 antibodies by means of an enzyme-linked immunosorbent assay. Seroprevalence varied amongst the five provinces sampled, ranging from 82.6% in the Eastern Province to 48.3% in Luapula Province. Seroprevalence also varied amongst the 11 districts sampled, ranging from 91.3% in Monze district of Southern Province to 22.8% in Mufulira district of the Copperbelt province. Overall, the seroprevalence of Newcastle disease in Zambian backyard chicken flocks has increased since the previous study conducted in 1994.

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Section: Discussionmentioning

confidence: 99%

Determination of the seroprevalence of Newcastle disease virus (avian paramyxovirus type 1) in Zambian backyard chicken flocks

Musako

Abolnik

2012

Onderstepoort J Vet Res

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“…In Zambia, NDV was first detected in 1952 in the Southern Province, where 15 outbreaks were recorded in that year, although the pathotypes of the isolates remained unknown [ 16 ]. By the early 1980s, velogenic NDV strains had been detected in different parts of the country, and ND was considered enzootic throughout the country [ 16 ]. Since then, the government enforced a vaccination policy in commercial poultry farms.…”

Section: Introductionmentioning

confidence: 99%

Phylogenetic Analysis of Newcastle Disease Virus Isolated from Poultry in Live Bird Markets and Wild Waterfowl in Zambia

Kalonda,

Saasa,

Kajihara

et al. 2024

Microorganisms

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Poultry production is essential to the economy and livelihood of many rural Zambian households. However, the industry is threatened by infectious diseases, particularly Newcastle disease virus (NDV) infection. Therefore, this study employed next-generation sequencing to characterise six NDV isolates from poultry in Zambia’s live bird markets (LBMs) and wild waterfowl. Four NDV isolates were detected from 410 faecal samples collected from chickens in LBMs in Lusaka and two from 2851 wild birds from Lochinvar National Park. Phylogenetic analysis revealed that the four NDVs from LBM clustered in genotype VII and sub-genotype VII.2 were closely related to viruses previously isolated in Zambia and other Southern African countries, suggesting possible local and regional transboundary circulation of the virus. In contrast, the two isolates from wild birds belonged to class I viruses, genotype 1, and were closely related to isolates from Europe and Asia, suggesting the possible introduction of these viruses from Eurasia, likely through wild bird migration. The fusion gene cleavage site motif for all LBM-associated isolates was 112RRQKR|F117, indicating that the viruses are virulent, while the isolates from wild waterfowl had the typical 112ERQER|L117 avirulent motif. This study demonstrates the circulation of virulent NDV strains in LBMs and has, for the first time, characterised NDV from wild birds in Zambia. The study further provides the first whole genomes of NDV sub-genotype VII.2 and genotype 1 from Zambia and stresses the importance of surveillance and molecular analysis for monitoring the circulation of NDV genotypes and viral evolution.

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Prevalence and evaluation of Hitchner B1 and V4 vaccines for the control of Newcastle disease in village chickens in Zambia

Alders

Inoue

Katongo³

1994

Preventive Veterinary Medicine

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A study on Newcastle disease virus pathotypes in Zambia

Cited by 3 publications

References 1 publication

Determination of the seroprevalence of Newcastle disease virus (avian paramyxovirus type 1) in Zambian backyard chicken flocks

Determination of the seroprevalence of Newcastle disease virus (avian paramyxovirus type 1) in Zambian backyard chicken flocks

Phylogenetic Analysis of Newcastle Disease Virus Isolated from Poultry in Live Bird Markets and Wild Waterfowl in Zambia

Prevalence and evaluation of Hitchner B1 and V4 vaccines for the control of Newcastle disease in village chickens in Zambia

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