This Special Issue highlights the latest enhancements in the abatement of noise and vibrations of aerospace and automotive systems. The reduction of acoustic emissions and the improvement of cabin interior comfort are on the path of all major transportation industries, having a direct impact on customer satisfaction and, consequently, the commercial success of new products. Topics covered in this Special Issue deal with computational, instrumentation and data analysis of noise and vibrations of fixed wing aircrafts, satellites, spacecrafts, automotives and trains, ranging from aerodynamically generated noise to engine noise, sound absorption, cabin acoustic treatments, duct acoustics and vibroacoustic properties of materials. The focus of this Special Issue is also related to industrial aspects, e.g.,: numerical and experimental studies have been performed for an existing and commercialized engine to enable design improvements aimed at reducing noise and vibrations; moreover, an optimization is provided for the design of low vibroacoustic volute centrifugal compressors and fans whose fluids should be strictly kept in the system without any leakage. Existing procedures and algorithms useful to reach the abovementioned objectives in the most efficient way are illustrated in the collected papers.