The aim of this work was to evaluate the different phases formed during solidification and after thermal aging of the as-welded 625 nickel-based alloy, as well as the influence of microstructural changes on the mechanical properties. The experiments addressed aging temperatures of 650 and 950 o C for 10, 100 and 200 h. The samples were analyzed by electron microscopy, microanalysis and X-ray diffraction in order to identify the secondary phases. Mechanical tests such as hardness, microhardness and Charpy-V impact test were performed. Nondestructive ultrasonic inspection was also conducted to correlate the signals with mechanical and microstructural properties. The results show that the alloy 625 when aged at 650 °C experienced microstructural changes that were responsible by the dissolution of Laves phase formed during the solidification and the appearance of fine carbides along the solidification grain boundaries. When aged at 950°C, the Laves phase was continuously dissolved and the excess Nb caused the precipitation of -phase (Ni 3 Nb), which was intensified at 10 hours of aging, with subsequent dissolution for longer periods such as 200 h. Even when subjected to significant microstructural changes, the mechanical properties, especially toughness, were not sensitive to the dissolution and/or precipitation of the secondary phases.