A study on the stability of bronopol in bronopol lotion by ion-paired reversed-phase high performance liquid chromatography

The Release of Formaldehyde upon Decomposition of 2-Bromo-2-nitropropan-1, 3-diol (Bronopol)

“…There have been several studies on the stability or degradation of FA-releasing substances, 16,17) but very little has been reported about the release of FA upon their decomposition. This paper is the first regarding the release of FA upon decomposition of BP.…”

Bacterial behaviors on polymer surfaces with organic and inorganic antimicrobial compounds

“…The amount of active bacteria degrades always with increasing time. 16,[33][34][35] Further, it has better ability in inhibiting bacterial biofilm formation under experimental conditions. Meanwhile, because organic antimicrobial reagents release from bulk PVC slowly, this greatly affects bio-film bacterial adherence and formation as well.…”

“…The results are shown in Table II and are also illustrated from some references. [16][17][18][19][20][21][22][33][34][35] Why do inorganic antimicrobial reagents not have good ability in inhibiting bacterial bio-film in spite of their excellent antibacterial ability? What does make so much difference between PVC samples containing organic and inorganic antimicrobial reagents?…”

Plasma surface modification of poly vinyl chloride for improvement of antibacterial properties

“…This phenomenon should be interpreted from the antibacterial mechanism of triclosan. Based on results reported recently [23][24][25], triclosan acts as a non-specific biocide by affecting the membrane structure and function of the bacteria. When it reacts with bacteria, triclosan forms a stable ternary complex by interacting with amino-acid residues of the enzyme active site.…”

“…1 are two types of compounds that exhibit immediate, persistent, broad-spectrum antimicrobial effectiveness as well as little toxicity in clinical use. They also deliver excellent biochemical and physical performances after plasma surface modification [23][24][25]. Therefore in this work, we determine the appropriate PIII treatment conditions to yield superior surface antibacterial properties and decrease the degree of bacteria adhesion on medical-grade PVC.…”