A study on the topological distribution of phospholipids in microsomal membranes of chick brain using phospholipase C and trinitrobenzenesulfonic acid

Dominski, J.; Binaglia, Luciano; Dreyfus, H.; Massarelli, R.; Mersel, Marcel; Freysz, L.

doi:10.1016/0005-2736(83)90123-2

Cited by 32 publications

(13 citation statements)

References 27 publications

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“…A novel prediction of the model is that the outer surface of the IV and MV represents the luminal side of the ER. This topology can explain the exposure of some phosphatidylserine, which is more abundant on the luminal side of the ER (Dominski et al, 1983; Fairn et al, 2011) on the surface of the MV (Cluett and Machamer, 1996) (Mercer and Helenius, 2008). …”

Section: A Model For Poxvirus Membrane Biogenesismentioning

confidence: 99%

Poxvirus membrane biogenesis

Moss

2015

Virology

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Poxviruses differ from most DNA viruses by replicating entirely within the cytoplasm. The first discernible viral structures are crescents and spherical immature virions containing a single lipoprotein membrane bilayer with an external honeycomb lattice. Because this viral membrane displays no obvious continuity with a cellular organelle, a de novo origin was suggested. Nevertheless, transient connections between viral and cellular membranes could be difficult to resolve. Despite the absence of direct evidence, the intermediate compartment (ERGIC) between the endoplasmic reticulum (ER) and Golgi apparatus and the ER itself were considered possible sources of crescent membranes. A break-through in understanding poxvirus membrane biogenesis has come from recent studies of the abortive replication of several vaccinia virus null mutants. Novel images showing continuity between viral crescents and the ER and the accumulation of immature virions in the expanded ER lumen provide the first direct evidence for a cellular origin of this poxvirus membrane.

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Section: A Model For Poxvirus Membrane Biogenesismentioning

confidence: 99%

Poxvirus membrane biogenesis

Moss

2015

Virology

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“…Besides phospholipids, plasma membranes contain a high amount of cholesterol, but the distribution of this lipid is still a subject of debate: some reports are in favour of an almost symmetrical repartition in the two leaflets (Blau and Pelletier et al, 1987Post et al, 1988Record et al, 1984Higgins and Evans, 1978Sessions and Horwitz, 1983Sessions and Horwitz, 1983Sessions and Horwitz, 1983 Olaisson et al, 1985Deutsch and Kelly, 1981Bollen and Higgins, 1980Dominski et al, 1983Buckland et al, 1978Marinetti et al, 1976Nilsson and Dallner, 1977 Crain and Marinetti, 1979Krebs et al, 1979Harb et al, 1981 an uneven distribution of cholesterol (Brasaemle et al, 1988;Fisher, 1976;Schroeder et al, 1991).…”

Section: Asymmetry In Various Membranes Plasma Membranesmentioning

confidence: 99%

Phospholipids in animal eukaryotic membranes: transverse asymmetry and movement

Zachowski

1993

Biochemical Journal

788

565

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“…A further consequence of our model is that the outer surface of the MV, which is derived from the IV, represents the luminal side of the ER. This topology can explain the exposure of phosphatidylserine, which is more abundant on the luminal side of the ER (47,48), on the surface of the MV (49).…”

Section: Discussionmentioning

confidence: 97%