A Study Protocol to Assess the Correlation of Endometrial Morphology with Concerned Hormone Levels in Patients of Abnormal Uterine Bleeding

Abstract

Background: Abnormal-uterine-bleeding (AUB) is caused due to numerous systemic or functional etiologies. Patients may come with metrorrhagia, menorrhagia, intermenstrual bleeding and polymenorrhea. The underlying pathology can be ascertained by histological variations of endometrium considering the age, the phase of menstrual cycle and the use of any exogenous hormones. This study aims to assess the correlation between endometrial changes and concerned hormone levels.
 Methodology: This will be a Prospective study conducted for two years in Histopathology Department of Pathology, JNMC, Wardha. Total 65 female patients with complaint of irregular uterine bleeding will be included in this study. The histomorphology patterns of endometrial lesions will be studied and classified according to WHO classification. The collected data will be analysed using appropriate statistical methods.
 Results: A Significant correlation is expected between endometrial changes and concerned hormone levels.
 Conclusion: Conclusion will be drawn from the results obtained from the study.