A study-screening of blood donors for blood transmissible diseases

Shinde, Sweety; Puranik, Gururaj

doi:10.1007/s12288-008-0006-y

Cited by 6 publications

(6 citation statements)

References 12 publications

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“…[7] More recently, a tertiary care hospital in Delhi reported that only 1% of healthcare workers were HBsAg-positive. [8] Other studies done in the various parts of India shows HBsAg prevalence of 1-1.7% in various studies, which is lower than the HBV carrier frequency of 2-4% in the general population. [9] This decreasing trend is most probably due to increasing awareness regarding these infections and hepatitis B vaccination.…”

Section: Discussionmentioning

confidence: 98%

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Low prevalence of hepatitis B and C infections among the healthcare workers despite low vaccination coverage for hepatitis B in Mumbai

et al. 2017

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Background:The risk of acquiring hepatitis B virus (HBV) and hepatitis C virus (HCV) infections through exposure to blood or its products and contact with other body fluids is high amongst health care workers (HCWs). Despite potential risks, a proportion of HCWs never get vaccinated. This study aimed to investigate the vaccination practices and the prevalence of HBV infection in HCWs. Aims: To determine the prevalence of HBV and HCV, their possible association with occupational and non-occupational risk factors. We also studied the prevalence of vaccination for hepatitis B in different subgroups of study population. Materials and Methods: In this cross-sectional study, total 1347 hospital staffs were screened for hepatitis B and hepatitis C. HBV is detected by HBsAg testing, and HCV is detected by anti-HCV testing by ELISA method. Positive results were confirmed by HBV DNA testing (Qualitative) and HCV RNA testing (Qualitative). A questionnaire used to collect data from study participants was pre-designed by the authors. Results: Out of total 1347 hospital staffs screened, 6 (0.4%) were HBsAg-positive and 2 (0.1%) were anti-HCV-positive. Only 54% had a history of complete vaccination, and 0.3% had incomplete vaccination. Vaccination coverage was highest in residents (76.7%), medical students (68.9%), nursing (66.1%), and teachers (61.4%) and lowest in servants (5.4%), office staff (6.6%), and lab technicians (24.3%). Awareness about the risk factor for transmission of HBV and HCV and complication related to them was 77.7%. It was highest in teachers (93.9%) and residents (97.8%), lowest in servants (16.3%). No statistically significant difference in the exposure to various risk factors among those who are HBsAg or anti-HCV-positive and HBsAg or anti-HCV-negative. Conclusions: The prevalence of HBV and HCV infection is not high in hospital staff than general population. Hepatitis B vaccination coverage was below expectation in all the subgroups even in resident doctors and teachers.

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Section: Discussionmentioning

confidence: 98%

“…Reports from India, [8,11] Pakistan, [3] Nepal, [2,12] Egypt, [13] Brazil, [14] and Nigeria [5] indicate that only 16-60% of HCW have received complete HBV immunization. In these countries, paramedics were more often unaware of HBV/HCV transmission and less often received HBV vaccination than doctors.…”

Section: Discussionmentioning

confidence: 99%

Low prevalence of hepatitis B and C infections among the healthcare workers despite low vaccination coverage for hepatitis B in Mumbai

et al. 2017

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“…[ 4 ] This article reviewed available literature from SSA, but many articles from Asia proved to suffer from the same shortcomings [ Table 2 ]. In articles published in the last 10 years on viral marker comparisons between VNRD and FRD in the Indian subcontinent, none carried out assay confirmation and only one examined the impact of age in epidemiologic data[ 34 35 36 37 38 39 40 41 42 43 ] and Table 2 . No studies account for the bias of repeat VNRDs in data analyses.…”

Section: Methodsmentioning

confidence: 99%

“…However, two of these articles did not find differences between the two types of donors. [ 36 40 ] The study stratifying for age found no difference between VNRD and FRD for HBsAg prevalence but significantly less in VNRD for anti-HCV though without confirmation. [ 42 ]…”

Section: Methodsmentioning

confidence: 99%

Family donors are critical and legitimate in developing countries

Allain¹,

Sibinga²

2016

Asian J Transfus Sci

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Introduction:For many years, family blood donors have been considered less safe than volunteer non-remunerated blood donors and actively discouraged by international organisations and affluent countries support agencies for developing countries. In addition to safety, pressure and coercion was considered unethical. However these assumptions were not supported by evidence.Aims of the study:To assemble recently collected evidence to reopen the assessment whether or not the ban of family blood donors is justified.Methods:Review of old and recent literature through Pubmed and references from identified articles.Results and Discussion:Viral marker data comparing confirmed seroprevalence in 1st time volunteer non-remunerated donors (VNRD) and family/replacement donors (FRD) corrected for gender and age, show no significant difference between the two groups. Evidence has been provided that for both VNRD and FAD benevolence is more appropriate than altruism. The two groups merge for psychological attitude to donation for which knowing someone needing transfusion is a powerful incentive to give blood. Excluding a life or death situation found in areas where severe blood shortage justifies replacement donation, pressures are exerted on both VNRD and FRD. There is no evidence of coercion of FRD. FRDs therefore meet all criteria for VNRD and are willing to become VNRD and to repeat donation. Ostracising FRD is illegitimate and damaging to the blood supply in resource poor areas. In some countries no difference is made between the two groups of donors representing similar populations asked to give blood in different circumstances.Conclusions:FRDs remain a critical source of volunteer, non-remunerated, blood meeting all classical criteria of VNRD that should be considered legitimate and indispensable at this point in time instead of discouraged.

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“…Prior to the availability of the hepatitis B vaccine, numerous cross-sectional surveys showed that HCWs had a three to five-fold higher seroprevalence of HBV infection than the general U.S. population. (7,11,12,13,14) This decreasing trend is most probably due to increasing awareness regarding these infections and hepatitis B vaccination. Out of 37 doctors, 32 were fully vaccinated and only one was a non-responder, in nursing staff out of 18 none had taken HBV vaccination but 38.9 %(7) had protective antiHBs levels.…”

Section: Discussionmentioning

confidence: 99%

HBV and HCV in Health care workers and students of a newly established Tertiary care hospital at Rishikesh: Prevalence and immunity status

Gupta¹,

Kaistha²,

Omar³

2020

Indian J Community Health

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Background: Hepatitis B and C cause serious infectious disease of the liver which affects millions of people worldwide. More than 2 billion people living today have been infected with Hepatitis B virus (HBV) at some time in their lives and about 350 million people are carriers of the virus. Aim: To detect HBV and HCV infection and assess HBV immunity status amongst healthcare workers, medical students and nursing students at AIIMS Rishikesh. Methods: 135 participants (Medical faculty, Nursing Faculty, Resident Doctors, laboratory technicians, laboratory attendants, medical and nursing students) were enrolled for the study. Serological tests HBsAg, anti-hepatitis C virus antibodies (anti-HCV), anti-HBs antibodies, were performed. None were positive for HBsAg 1.5% were positive for Anti HCV antibodies and 61.75% had protective levels of antiHBs. Conclusion: HBV vaccination and screening for HBV, HCV, and anti-HBs of all HCW and students at time of entry should be done. Yearly screening thereafter should be done to check as follow up. Regular training on HBV vaccination and safe practices should be emphasized at all levels of HCW.

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A study-screening of blood donors for blood transmissible diseases

Cited by 6 publications

References 12 publications

Low prevalence of hepatitis B and C infections among the healthcare workers despite low vaccination coverage for hepatitis B in Mumbai

Low prevalence of hepatitis B and C infections among the healthcare workers despite low vaccination coverage for hepatitis B in Mumbai

Family donors are critical and legitimate in developing countries

HBV and HCV in Health care workers and students of a newly established Tertiary care hospital at Rishikesh: Prevalence and immunity status

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