The volumetric computed tomography (CT) dose index (CTDIvol) is the measure of output displayed on CT consoles relating to dose within a standard phantom. This gives a false impression of doses levels within the tissues of smaller patients in Southeast Asia. A size-specific dose estimate (SSDE) can be calculated from the CTDIvol to provide an assessment of doses at specific positions within a scan using size-specific conversion factors. SSDE is derived using the water equivalent diameter (D
w) of the patient, but calculation of D
w requires sophisticated computer software. This study aimed to evaluate relationships between D
W and effective diameter (D
Eff), which can be measured more readily, in order to estimate SSDE at various positions within a routine clinical abdomen and pelvis CT examination for Thai patients. An in-house ImageJ algorithm was developed to measure D
w, effective diameter (D
Eff), and SSDE on CT slices located at the heart, liver, kidneys, colon, and bladder, on 181 CT examinations of abdomen and pelvis. Relationships between D
Eff and D
w were determined, and values of organ absorbed dose using D
Eff were estimated. This approach was validated using a second cohort of 54 patients scanned on a different CT scanner. The results revealed that ratios between D
Eff and D
w at the heart level were 1.11–1.13 and those for the others were about 1.00. Additionally, the SSDE/CTDIvol ratio was estimated for each organ in terms of exponential functions using the relationships between D
w and D
Eff for individual organs. In summary, this study proposed a simple method for estimation of organ absorbed doses for Southeast Asian patients undergoing abdomen and pelvis CT examinations where sophisticated computer software is not available.