A sulfamethoxazole molecularly imprinted two-dimensional photonic crystal hydrogel sensor

Cao, Yunlei; Liu, Genqi; Zheng, Bingqing; Wang, Xinlong; Li, Huanhuan; Wang, Gang; Zhao, Lingli; Wang, Yue

doi:10.1039/d1sm00176k

Cited by 20 publications

(15 citation statements)

References 29 publications

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“…The diffraction images corresponding to different values of P reveal diffraction rings indicative of polycrystalline microstructures without any preferred domain orientation, as reported for other hard sphere and hard sphere-like systems. [47][48][49] As such, there are no distinguishable Bragg peaks. During compression, the position of the diffraction ring remains nearly unchanged (D SALS c-c = 719 AE 15 nm).…”

Section: Application Of Lt-sals To Other Colloidal Systemsmentioning

confidence: 99%

Compression of colloidal monolayers at liquid interfaces: in situ vs. ex situ investigation

et al. 2023

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Section: Application Of Lt-sals To Other Colloidal Systemsmentioning

confidence: 99%

Compression of colloidal monolayers at liquid interfaces: in situ vs. ex situ investigation

et al. 2023

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“…A 2D molecularly imprinted photonic crystal hydrogels (MIPCH) sensor was made by Cao et al in order to sense sulfamethoxazole (SMZ) [ 114 ]. Their sensor was relatively similar to the previous example except their binding pocket was made specifically for SMZ.…”

Section: Drug Sensingmentioning

confidence: 99%

“…( B ) Dependence of the normalized diffraction spectra of SMZ–MIPCH on the SMZ concentration. (The measurement angle between the probe and the normal range to MIPCH is 21°) (Reprinted with permission from [ 114 ]. Copyright 2021 Royal Chemical Society).…”

Section: Figurementioning

confidence: 99%

Hydrogel-Based Biosensors

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et al. 2022

Gels

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There is an increasing interest in sensing applications for a variety of analytes in aqueous environments, as conventional methods do not work reliably under humid conditions or they require complex equipment with experienced operators. Hydrogel sensors are easy to fabricate, are incredibly sensitive, and have broad dynamic ranges. Experiments on their robustness, reliability, and reusability have indicated the possible long-term applications of these systems in a variety of fields, including disease diagnosis, detection of pharmaceuticals, and in environmental testing. It is possible to produce hydrogels, which, upon sensing a specific analyte, can adsorb it onto their 3D-structure and can therefore be used to remove them from a given environment. High specificity can be obtained by using molecularly imprinted polymers. Typical detection principles involve optical methods including fluorescence and chemiluminescence, and volume changes in colloidal photonic crystals, as well as electrochemical methods. Here, we explore the current research utilizing hydrogel-based sensors in three main areas: (1) biomedical applications, (2) for detecting and quantifying pharmaceuticals of interest, and (3) detecting and quantifying environmental contaminants in aqueous environments.

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“…The result demonstrated that although the reported LOD values of MIP-sensors range from 103 to 105 nM, the lowest values are still comparable with the LOD values reported for the HPLC technique (0.031–0.047 nM) [ 176 ]. Moreover, an even lower LOD value of 107 nM was reported for the molecularly imprinted two-dimensional photonic crystal hydrogel sensor for the label-free recognition of sulfamethoxazole [ 105 ]. Nevertheless, despite these promising results achieved for MIP sensors on the laboratory scale, the large-scale use is still problematic, due to several challenges in the synthesis (see Section 5 ), mass-scale production and commercialisation.…”

Section: Conclusion and Future Perspectivesmentioning

confidence: 99%

Advances in Detection of Antibiotic Pollutants in Aqueous Media Using Molecular Imprinting Technique—A Review

et al. 2022

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Antibiotics constitute one of the emerging categories of persistent organic pollutants, characterised by their expansion of resistant pathogens. Antibiotic pollutants create a major public health challenge, with already identifiable detrimental effects on human and animal health. A fundamental aspect of controlling and preventing the spread of pollutants is the continuous screening and monitoring of environmental samples. Molecular imprinting is a state-of-the-art technique for designing robust biomimetic receptors called molecularly imprinted polymers (MIPs), which mimic natural biomolecules in target-selective recognition. When integrated with an appropriate sensor transducer, MIP demonstrates a potential for the needed environmental monitoring, thus justifying the observed rise in interest in this field of research. This review examines scientific interventions within the last decade on the determination of antibiotic water pollutants using MIP receptors interfaced with label-free sensing platforms, with an expanded focus on optical, piezoelectric, and electrochemical systems. Following these, the review evaluates the analytical performance of outstanding MIP-based sensors for environmentally significant antibiotics, while highlighting the importance of computational chemistry in functional monomer selection and the strategies for signal amplification and performance improvement. Lastly, the review points out the future trends in antibiotic MIP research, as it transits from a proof of concept to the much demanded commercially available entity.

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A sulfamethoxazole molecularly imprinted two-dimensional photonic crystal hydrogel sensor

Abstract: In this paper, a molecularly imprinted two-dimensional photonic crystal hydrogels sensor (SMZ-MIPCH) for sensitive and label-free recognition of sulfamethoxazole (SMZ) was prepared. Investigating SMZ-MIPCH sensor response performance by measuring the...

Cited by 20 publications

References 29 publications

Compression of colloidal monolayers at liquid interfaces: in situ vs. ex situ investigation

Compression of colloidal monolayers at liquid interfaces: in situ vs. ex situ investigation

Hydrogel-Based Biosensors

Advances in Detection of Antibiotic Pollutants in Aqueous Media Using Molecular Imprinting Technique—A Review

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