A Summary of Rare Sites of Metastasis Secondary to Differentiated Thyroid Cancer

Khorjekar, Gauri; Kłubo-Gwieździńska, Joanna; Nostrand, Douglas Van; Wartofsky, Léonard

doi:10.1007/978-1-4939-3314-3_66

Cited by 2 publications

(1 citation statement)

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“…Around 31 cases of adrenal metastasis have been reported so far in literature. Almost all those patients had advanced disseminated disease 6. To our knowledge, only one case has been reported so far with adrenal metastasis as the presenting feature.…”

Section: Discussionmentioning

confidence: 92%

Unilateral adrenal mass as the sole initial manifestation of differentiated thyroid cancer

Sampathkumar¹,

Arun

Bindhu

et al. 2017

BMJ Case Reports

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Unilateral adrenal metastases without disseminated disease has rarely been reported in differentiated thyroid carcinoma (DTC). A 72-year-old female presented with vague abdominal discomfort and loss of appetite of 2 months duration. She had undergone left hemithyroidectomy for a benign thyroid nodule 18 years ago. A contrast CT of the abdomen showed a large left adrenal mass measuring 11×9 cm, suspicious of adrenocortical carcinoma. Hormonal evaluation was in keeping with a non-functional tumour. The patient underwent left adrenalectomy, histopathology of which revealed metastatic well-differentiated thyroid carcinoma. Ultrasound of thyroid done postoperatively showed a subcentimetric hypoechoic lesion with increased vascularity and microcalcifications in the right thyroid bed. Histopathology from a completion thyroidectomy specimen was consistent with follicular variant of papillary thyroid carcinoma. She was treated with high-dose radioiodine ablation therapy and has remained disease-free on follow-up for more than a year.

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Section: Discussionmentioning

confidence: 92%