Ann Mol Genet Med 2020
DOI: 10.17352/amgm.000007
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A summary of the molecular testing recommended in acute myeloid leukemia

Abstract: Advances in Next-Generation Sequencing technologies (NGS) are revealing germline and somatic mutations that, together with karyotype, determine the diagnosis and subtype of Acute Myeloid Leukemia (AML). Molecular testing is also essential for the genetic risk stratifi cation of patients with AML, in particular for those with normal karyotype AML (CN-AML), a large and highly heterogeneous group of patients. Patients determined to be at high risk could benefi t from a more aggressive fi rst-line therapy, or a mo… Show more

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References 42 publications
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