Microwave imaging has become an active research area in recent years, owing primarily to advancements in detecting the early stages of cancer. The study aimed to create a high-gain compact Vivaldi Tapered Slot antenna (VTSA) for microwave imaging in medical applications and also aims to address several challenges in the development of microwave imaging (MWI) technology for medical applications. These challenges include the ability to detect and identify abnormalities in human tissue and considering safe Specific Absorption Rate (SAR) limits for patients, the approach of balancing of penetration and resolution can be done on the design. The antenna operates at frequencies ranging from 1.7 to 3.1 GHz and is built on a low-cost Flame Retardant-4 (FR-4) substrate with a thickness of 1.6 mm. A compact exponential VTSA is initially presented while designing the proposed antenna for broad impedance bandwidth performances. The simulation used a back-to-back linear array of antennas with or without a phantom, specifically a without phantom (only antennas), a water phantom (cube shape), and an anomaly inside the water phantom. The results revealed a significant shift in the signal graph between the three results, indicating a difference in values between the three simulations. A transient domain solver calculation was used in the simulation. The designed antenna improved a gain of 6.09 dBi and a SAR of 0.326 W/kg by maximizing the edges of the exponential in the tapered section and the feedline slot area. The antenna exhibits differences in scattering parameters on each simulation of anomalies across the required frequency range. The result finds suitability of the experiment and simulation in assessing the microwave imaging capabilities. With the data presented, simulated antennas can be used for microwave imaging. The next study should aim on making a suitable imaging system with dimensions that supported in the antenna range and specifications.