A surface-enhanced Raman scattering active core/shell structure based on enzyme-guided crystal growth for bisphenol A detection

Xu, Zhou; Wang, Rong; Mei, Bo; Ding, Li; Wang, Libing; Chen, Mao-Long; Cheng, Yunhui

doi:10.1039/c7ay02776a

Cited by 7 publications

(3 citation statements)

References 38 publications

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“…This method, which was demonstrated to detect BPA in bottled water in 15 min, demonstrated a linear dynamic range of 0.01-1 ng/mL and a LOD of 2.8 pg/mL. Finally, Xu et al used silver-coated gold nanostars (AgNS), which interacted with glucose oxidase modified BPA aptamer (Jo et al, 2011) to generate a SERS signal in the presence of BPA (Xu et al, 2018). Briefly, the BPA aptamer modified with glucose oxidase was incubated with the AuNS.…”

Section: Industrial Byproductsmentioning

confidence: 99%

Aptamer-Based Biosensors for Environmental Monitoring

2020

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Due to their relative synthetic and chemical simplicity compared to antibodies, aptamers afford enhanced stability and functionality for the detection of environmental contaminants and for use in environmental monitoring. Furthermore, nucleic acid aptamers can be selected for toxic targets which may prove difficult for antibody development. Of particular relevance, aptamers have been selected and used to develop biosensors for environmental contaminants such as heavy metals, small-molecule agricultural toxins, and water-borne bacterial pathogens. This review will focus on recent aptamer-based developments for the detection of diverse environmental contaminants. Within this domain, aptamers have been combined with other technologies to develop biosensors with various signal outputs. The goal of much of this work is to develop cost-effective, user-friendly detection methods that can complement or replace traditional environmental monitoring strategies. This review will highlight recent examples in this area. Additionally, with innovative developments such as wearable devices, sentinel materials, and lab-on-a-chip designs, there exists significant potential for the development of multifunctional aptamer-based biosensors for environmental monitoring. Examples of these technologies will also be highlighted. Finally, a critical perspective on the field, and thoughts on future research directions will be offered.

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Section: Industrial Byproductsmentioning

confidence: 99%

Aptamer-Based Biosensors for Environmental Monitoring

2020

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“…SERS is a powerful analytical technique that has already been proven to be particularly effective in chemical biology and medicine. , Essentially, SERS can be described as amplified Raman scattering by the presence of a plasmonic structure in the close vicinity of the target analytes . In such a case, direct SERS detection of biomolecules, such as proteins, peptides, and metabolites, in a biological system is inherently affected by the materials with stronger affinity for metallic SERS plasmonic substrates, and analysis targets, like proteins, usually existing as complicated structures that further render the spectrum intricate and the analysis difficult. , To address these issues and make the best of SERS advantages to detect biological species, indirect SERS sensors can be established through analysis of the changes of SERS spectra of modified Raman signal molecules before and after reaction with target analytes on plasmonic nanostructures. , To keep the quick and ultrasensitive merits of the SERS technique, the reaction between Raman signal molecules and analytes needs to be specific, quick, not sensitive to water and oxygen, high yielding, etc., which make the click reaction come forward . Click reaction represents a rapid, simple, selective, and high-yielding bioorthogonal reaction that was tolerant of various functional groups and occurred under mild synthetic conditions, and it is also easily capable of immobilizing target molecules on the SERS sensor surface. , …”

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confidence: 99%

“…18,19 To address these issues and make the best of SERS advantages to detect biological species, indirect SERS sensors can be established through analysis of the changes of SERS spectra of modified Raman signal molecules before and after reaction with target analytes on plasmonic nanostructures. 20,21 To keep the quick and ultrasensitive merits of the SERS technique, the reaction between Raman signal molecules and analytes needs to be specific, quick, not sensitive to water and oxygen, high yielding, etc., which make the click reaction come forward. 22 Click reaction represents a rapid, simple, selective, and high-yielding bioorthogonal reaction that was tolerant of various functional groups and occurred under mild synthetic conditions, 23 and it is also easily capable of immobilizing target molecules on the SERS sensor surface.…”

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confidence: 99%

Click-Reaction-Triggered SERS Signals for Specific Detection of Monoamine Oxidase B Activity

Wang

et al. 2020

Anal. Chem.

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Human monoamine oxidases (MAOs) play important roles in maintaining the homeostasis of biogenic amines. One of its isoforms, monoamine oxidase B (MAOB), is thought to be involved in several neurodegenerative diseases, which make the selective detection of MAOB activity essential. In this work, a novel surface-enhanced Raman scattering (SERS) sensor was fabricated and the MAOB activity was specifically determined by detecting the SERS signals of an enzyme-catalyzed reaction product via an amine–aldehyde click reaction. This process was simply achieved by coating core–shell gold–silver nanoparticles (Au@Ag NPs) on 3-aminopropyl aminopropyl triethoxysilane (APTES)-modified glass, and then, a monolayer of cysteamine (CA) was attached to the nanoparticle surface as a linker through Ag–S bonds. Using phenethylamine (PA) as a specific substrate of MAOB, the enzyme product phenylacetaldehyde (PAA) will produce significant Raman signals via the amine–aldehyde click reaction with CA, while other molecules, such as MAOB and PA, have no signal output because they cannot form close interaction with nanoparticles due to the existence of a CA layer. This sensor was further used for the specific determination of MAOB activity in clinical blood samples and the MAOB inhibitor assessment successfully. Meanwhile, by changing the click reaction types and taking advantage of the SERS fingerprint peaks for the specific click reaction products, this strategy offers huge potential to detect multiple enzyme activities simultaneously and can be used for new click reaction screening, enzyme-related disease diagnosis, drug screening, and clinical diagnosis.

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Monolithic 3D structural-substrate SERS sensing platform for ultrasensitive and highly-specific analysis of trace bisphenol A

Li,

Xie,

Chi

et al. 2024

Talanta

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A surface-enhanced Raman scattering active core/shell structure based on enzyme-guided crystal growth for bisphenol A detection

Abstract: Herein, a universal surface-enhanced Raman scattering (SERS) detection platform based on enzyme-guided crystal growth has been fabricated for the first time.

Cited by 7 publications

References 38 publications

Aptamer-Based Biosensors for Environmental Monitoring

Aptamer-Based Biosensors for Environmental Monitoring

Click-Reaction-Triggered SERS Signals for Specific Detection of Monoamine Oxidase B Activity

Monolithic 3D structural-substrate SERS sensing platform for ultrasensitive and highly-specific analysis of trace bisphenol A

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