A surface modification strategy on silicon nitride for developing biosensors

Diao, Jinpian; Ren, Dacheng; Engstrom, J. R.; Lee, Kelvin H.

doi:10.1016/j.ab.2005.05.010

Cited by 80 publications

(48 citation statements)

References 23 publications

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“…Since PD has exhibited hydrophilic tendencies, it may again be expected that PD trypsin adhesion may be low. Despite this, it is not clear what the difference will be, since the unfunctionalised silicon nitride probe used as the control is also hydrophilic with a water contact angle of 32 ± 12° [36]. Therefore, it is important to understand the interactions of PD with synthetic materials, such as polymers used in biomedical applications.…”

Section: Introductionmentioning

confidence: 99%

Probing polydopamine adhesion to protein and polymer films: microscopic and spectroscopic evaluation

2017

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Polydopamine has been found to be a biocompatible polymer capable of supporting cell growth and attachment, and to have antibacterial and antifouling properties. Together with its ease of manufacture and application, it ought to make an ideal biomaterial and function well as a coating for implants. In this paper, atomic force microscope was used to measure the adhesive forces between polymer-, protein-or polydopamine-coated surfaces and a silicon nitride or polydopamine-functionalised probes. Surfaces were further characterised by contact angle goniometry, and solutions by circular dichroism. Polydopamine was further characterised with infrared spectroscopy and Raman spectroscopy. It was found that polydopamine functionalisation of the atomic force microscope probe significantly reduced adhesion to all tested surfaces. For example, adhesion to mica fell from 0.27 ± 0.7 to 0.05 ± 0.01 nN nm -1 . The results suggest that polydopamine coatings are suitable to be used for a variety of biomedical applications.

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Section: Introductionmentioning

confidence: 99%

Probing polydopamine adhesion to protein and polymer films: microscopic and spectroscopic evaluation

2017

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“…184 Diao et al successfully produced monolayers of APTES on silicon nitride with contact angles of AE5 comparable to that obtained on silicon wafers by Janssen et al 103,185 Wang et al investigated SAM formation on silicon nitride using four silanes; OTS, octyltrichlorosilane, chlorodimethyloctadecylsilane and octadecyltrimethoxysilane. 17 It Fig.…”

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confidence: 85%

Challenges and developments of self-assembled monolayers and polymer brushes as a green lubrication solution for tribological applications

et al. 2015

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ab Self-assembled monolayers (SAMs), after originally being investigated due to their functions in changing surface wettability, have been significantly developed over the years. Many types of SAMs have been developed on a variety of substrates. However their formation mechanism, rate and quality are found to be influenced by many factors. A range of SAMs including single-and multi-component are included in this review with focus on the nano and macro tribological properties. More recently, surface initiated polymer brushes, i.e. macromolecular assemblies attached to a substrate, have emerged to be an alternative and promising method for surface modification. The ability to tether these macromolecules to tribological contacts is key to their resistance to shear under loaded contacts. This review also covers atom transfer radical polymerisation (ATRP) and the role of this technique in developing new lubrication solutions. Particular care has been taken to include the development of lubrication solutions for silicon nitride due to the importance of this material as an engineering ceramic. This paper reviews the stateof-the-art development of SAMs and polymer brushes especially the potential opportunities and challenges in applying them in tribological contacts as a lubrication solution.

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“…Compared to spin-casting or dip coating methods, electrochemistry offers several advantages such as film thickness and porosity controls. 3-APTES which is among the most widely used chemicals in direct surface modification (Diao et al, 2005) based on silanization for biomolecule immobilization (Blasi et al, 2005), was rarely used until now for biosensor applications as chemically modified electrodes (Pauliukaite et al, 2005;Kandimalla et al, 2005). The present research seeks to explore on the basis of the Figure 1, the electrochemical behavior of pure or diluted nonaqueous 3-APTES based electrolytes for the preparation of ultra thin 3-APTES films on gold surfaces.…”

Section: Cathodic Reduction Of 3-aminopropyltriethoxy Silanementioning

confidence: 99%

Electrodeposition of Insulating Thin Film Polymers from Aliphatic Monomers as Transducers for Biosensor Applications

Gharbi¹,

Herlem²

2011

Biosensors - Emerging Materials and Applications

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A surface modification strategy on silicon nitride for developing biosensors

Cited by 80 publications

References 23 publications

Probing polydopamine adhesion to protein and polymer films: microscopic and spectroscopic evaluation

Probing polydopamine adhesion to protein and polymer films: microscopic and spectroscopic evaluation

Challenges and developments of self-assembled monolayers and polymer brushes as a green lubrication solution for tribological applications

Electrodeposition of Insulating Thin Film Polymers from Aliphatic Monomers as Transducers for Biosensor Applications

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