A survey of 499 patients with acute anuric renal insufficiency

Balsløv, Jørgen T.; Jørgensen, Hans Ejsing

doi:10.1016/0002-9343(63)90084-6

Cited by 122 publications

(22 citation statements)

References 16 publications

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“…This conclusion agrees well with the finding of Munck, Lassen, Deetj en, and Kramer (46), that both cortical and renal venous oxygen saturation remained relatively high even during severe hemorrhagic hypotension, and is further supported by the survival of all dogs in the present series without evidence of renal failure. The fact that uncomplicated hemorhagic shock in man practically never leads to acute anuric renal failure (47) suggests a vascular response in the human kidney similar to that observed here in dogs.…”

Section: Discussionsupporting

confidence: 75%

Effect of hemorrhage and retransfusion on intrarenal distribution of blood flow in dogs

Aukland¹,

Wolgast²

1968

J. Clin. Invest.

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A B S T R A C T Distribution of intrarenal blood flow was studied in 12 dogs anesthetized with Nembutal. Medullary blood flow was estimated by local clearance of hydrogen gas from the outer medulla measured polarographically with needleshaped platinum electrodes, and by local clearance of 85Kr and mean transit time of 32P-labeled erythrocytes measured with a small semiconductor detector placed in the outer medulla. Cortical blood flow was estimated from cortical red cell transit time and from total renal blood flow measured by electromagnetic flowmeter.Bleeding to a mean arterial pressure of 50-65 mm Hg in the course of 8-20 min reduced cortical and medullary blood flow on the average to the same extent. In half of the experiments both cortical and medullary blood flow were reduced proportionately less than mean arterial pressure during the first half hour of bleeding. Maintenance of mean arterial pressure at 50-65 mm Hg in all cases led to progressive reduction of both cortical and medullary blood flow, out of proportion to the reduction of arterial pressure. A two step bleeding procedure used in two experiments also led to uniform reduction of renal blood flow. Reinfusion of blood after 2-3 hr of hypotension increased total renal blood flow to an average of 82% and outer medullary hydrogen clearance to an average of 92%o of control values. All dogs survived the experiment without evidence of renal failure.

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Section: Discussionsupporting

confidence: 75%

Effect of hemorrhage and retransfusion on intrarenal distribution of blood flow in dogs

Aukland¹,

Wolgast²

1968

J. Clin. Invest.

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“…There has been no improvement in survival with time, either in our patients or in those reported in the literature [5][6][7][8][9][10][11][12][13][14], A similar finding has been observed in all patients dialyzed for acute tubular necrosis [3]. Thus, patients dialyzed in the early pioneer days of acute dialysis, from 1945 through I960, had the same prognosis as the patients dialyzed in the 60s and 70s [3,[17][18][19], Older age is not responsible for this; rather it is believed that current patients have more serious underlying medical diseases.…”

Section: Discussionsupporting

confidence: 81%

Acute Renal Failure Complicating Aortic Aneurysm Surgery

Gornic

Kjellstrand²

1983

Nephron

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“…All or combination of theses mechanism were responsible for cerebral dysfunction due to liver, kidney or lung disease. Balslor et al (1965) 8 observed that mortality was 34% in patients with blood urea less than 300mg% and 78% in cases with blood urea above 500 mg%. Inspite of extensive work on uremia until today the exact etiopathological agent responsible for the clinical toxicity of uremia could not be single out.…”

Section: Resultsmentioning

confidence: 99%