A survey of anthelmintic resistance in nematodes of sheep in the netherlands

Borgsteede, F.H.M.; Pekelder, J. J.; Dercksen, D.; Sol, J.; Vellema, P.; Gaasenbeek, C. P. H.; Linden, J. N. van der

doi:10.1080/01652176.1997.9694765

Cited by 20 publications

(6 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(Table 2). According to Borgsteede et al (1997), in Holland, when using FECRT, resistance to benzimidazoles affected 84% of the sheep farms used in the …”

Section: Discussionmentioning

confidence: 99%

Anthelmintic resistance in trichostrongylid nematodes of sheep farms in Northwest Spain

et al. 2006

View full text Add to dashboard Cite

A survey to determine the prevalence of anthelmintic resistance in nematode parasites of sheep against the three main families of anthelmintics (benzimidazoles, macrocyclic lactones and imidazothiazoles) was carried out from January 1999 to December 2003 involving 85 flocks in Northwest (NW) Spain. In the study on prevalence of resistance to benzimidazoles, faecal egg count reduction test (FECRT) showed there was resistance in 8 (12.7%) flocks, 1 (1.6%) was suspected, and 54 (85.7%) were susceptible. The results indicated that 9 flocks (34.61%) showed resistance, 1 (3.85%) showed suspected resistance, and 16 (61.54%) were susceptible to the imidazothiazoles. Against macrocyclic lactones, resistance was observed in 8 flocks (15.69%), 4 (7.84%) showed suspected resistance and 39 (76.47%) were susceptible. None of the flocks used in the study showed resistance to the three families of anthelmintics. Nevertheless, six were recorded as resistant or suspected of being resistant to two of these families of anthelmintics. Egg hatch assay (EHA) and FECRT were carried out jointly on 61 flocks, although EHA was done on a total of 83 farms. The results showed that 15 (18.07%) of the 83 flocks were resistant, with egg death 50 over 0.1 microg/ml thiabendazole, and 68 (81.93%) were susceptible to benzimidazoles. When the results between FECRT and EHA were compared, both techniques showed good correlation in field studies. Faecal cultures performed pre- and post-treatment indicated that Teladorsagia and Trichostrongylus were the main genera.

show abstract

“…(Table 2). According to Borgsteede et al (1997), in Holland, when using FECRT, resistance to benzimidazoles affected 84% of the sheep farms used in the …”

Section: Discussionmentioning

confidence: 99%

Anthelmintic resistance in trichostrongylid nematodes of sheep farms in Northwest Spain

et al. 2006

View full text Add to dashboard Cite

show abstract

“…Since reversion of resistant strains to susceptibility is likely to be very slow (Jackson 1993), the use of alternative drugs, together with non‐chemotherapeutical measures, is clearly needed. The other broad spectrum classes of anthelmintics include the avermectin/milbemycin and levamisole/pyrantel‐morantel groups, for which there are no, or very few, cases of resistant nematodes recorded on goat or sheep farms in Europe (Jackson and others 1992, Hong and others 1996, Borgsteede and others 1997). Ivermectin is not licensed for use in goats in France and pyrantel is not fully satisfactory as the spectrum of this drug is limited to gastrointestinal nematodes and the efficacy against Trichostrongylus colubriformisy even at a double standard dose rate, is less than 62 per cent (Chartier and others 1995).…”

Section: Group Haemonchus Contortus Teladorsagia Circumcincta Trichosmentioning

confidence: 99%

Efficacy and pharmacokinetics of levamisole hydrochloride in goats with nematode infections

et al. 2000

View full text Add to dashboard Cite

The release of tumor necrosis factor-a, interleukin-1, interleukin-6 and prostaglandin E2 in bovine Kupffer cells stimulated with bacterial lipopolysaccharide. Veterinary Immunology and Immunopathology 66,301-307 Efficacy and pharmacokinetics of levamisole hydrochloride in goats with nematode infections _1u,-q M S 6 6.-I Group Control Mean Levamisole hydrochloride (1 x 12 mg/kg) Mean (% efficacy) Levamisole hydrochloride (2 x 6 mg/kg, 10 hours apart) Mean (% efficacy)

show abstract

“…Argentina BZs, LEV, IVM [24] Australia Ops, BZs, LEV, TBZ, OXF, Closantel, Morantel [19,20] Belgium BZs [25] Brazil BZs, LEV, IVM, Closantel [24] France BZs, LEV [26] Germany IVM,BZs, Pyrantel tarterate, FEN, Febantel, OXF, LEV, TBZ, ALB, MBZ [27] India BZs, IVM, FEN, Morantel, Closantel, LEV, Thiophanate, [28] Kenya BZs, LEV, RAF, FEN, IVM [29] Malaysia BM Z , LEV S , IVM, Moxidectin, Closantel [25] Netherlands OXF S , LEV S , BM Z , IVM [30] New Zealand BM Z , LEV S , IVM [18,31] Pakistan OXF S , LEV S , ALB, IVM [32,33] Paraguay BM Z , LEV S , IVM [34] South Africa BM Z , IVM, RAF, Closantel [35] Uruguay BM Z , LEV S , IVM [36] United State of America FEN, IVM, Pyrantel pamoate, LEV S , TB Z , [37,38] Zimbabwe RAF, BM Z , LEV S , [39] ALB = Albendazole, BM Z = Benzimidazoles, FEN=Fenbendazole, IVM = Ivermectin, LEV s = Levamisole, OXF S =Oxfendazoles, RAF = Rafoxanide, and TB Z = Thiabendazole. nematode.…”

Section: Anthelmintic Drugs Reference(s)mentioning

confidence: 99%

Anthelmintic Drug Resistance in Livestock: Current Understanding and Future Trends

Malik¹,

Sajid²,

Abbas³

et al. 2022

Parasitic Helminths and Zoonoses - From Basic to Applied Research

View full text Add to dashboard Cite

Anthelmintic, ectoparasiticides (insecticides, acaricides), and antiprotozoal chemotherapeutic drugs target parasites. Chenopodium oil like alkaloids, arsenic compounds, cupric sulfate, nicotine, and cupric silicate were used to destroy nematodes. Unfortunately, these chemicals were less effective and less safe for livestock. The four major groups of broad-spectrum antinematodal compounds are macrocyclic lactones such as milbemycins/ivermectin, benzimidazole/pro-benzimidazole, tetrahydro pyrimidines such as morantel, pyrantel tartrate, and imidazothiazoles such as tetramisole and levamisole. The various factors responsible for gastrointestinal (GI) parasitism make it difficult to develop effective control measures, to the best of our knowledge. Hence, an effective strategy for the control of parasitic diseases that do not solely rely on anthelmintic therapies needs to be developed at the regional level, based on the epidemiology of the disease. This book chapter aims to elaborate on the various other ways to control parasitic diseases due to Anthelmintic drug resistance.

show abstract

A survey of anthelmintic resistance in nematodes of sheep in the netherlands

Cited by 20 publications

References 20 publications

Anthelmintic resistance in trichostrongylid nematodes of sheep farms in Northwest Spain

Anthelmintic resistance in trichostrongylid nematodes of sheep farms in Northwest Spain

Efficacy and pharmacokinetics of levamisole hydrochloride in goats with nematode infections

Anthelmintic Drug Resistance in Livestock: Current Understanding and Future Trends

Contact Info

Product

Resources

About