A Survey of Endophytic Fungi Associated with High-Risk Plants Imported for Ornamental Purposes

Gioia, Laura; d’Errico, Giada; Sinno, Martina; Ranesi, Marta; Woo, Sheridan L.; Vinale, Francesco

doi:10.3390/agriculture10120643

Cited by 10 publications

(2 citation statements)

References 154 publications

(113 reference statements)

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“…There has been growing interest in endophytic organisms isolated from plants, producing diverse secondary metabolites with different biological activities reported in recent literature [ 5 , 60 ]. Genus Albizia has been reported as a rich source of endophytic fungi [ 61 ] that have valuable bioactivities, including antimicrobial [ 62 ], cytotoxic [ 63 ] and antioxidant [ 64 ].…”

Section: Discussionmentioning

confidence: 99%

Identification of Antibacterial Metabolites from Endophytic Fungus Aspergillus fumigatus, Isolated from Albizia lucidior Leaves (Fabaceae), Utilizing Metabolomic and Molecular Docking Techniques

et al. 2022

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The rapid spread of bacterial infection caused by Staphylococcus aureus has become a problem to public health despite the presence of past trials devoted to controlling the infection. Thus, the current study aimed to explore the chemical composition of the extract of endophytic fungus Aspergillus fumigatus, isolated from Albizia lucidior leaves, and investigate the antimicrobial activity of isolated metabolites and their probable mode of actions. The chemical investigation of the fungal extract via UPLC/MS/MS led to the identification of at least forty-two metabolites, as well as the isolation and complete characterization of eight reported metabolites. The antibacterial activities of isolated metabolites were assessed against S. aureus using agar disc diffusion and microplate dilution methods. Compounds ergosterol, helvolic acid and monomethyl sulochrin-4-sulphate showed minimal inhibitory concentration (MIC) values of 15.63, 1.95 and 3.90 µg/mL, respectively, compared to ciprofloxacin. We also report the inhibitory activity of the fungal extract on DNA gyrase and topoisomerase IV, which led us to perform molecular docking using the three most active compounds isolated from the extract against both enzymes. These active compounds had the required structural features for S. aureus DNA gyrase and topoisomerase IV inhibition, evidenced via molecular docking.

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Section: Discussionmentioning

confidence: 99%

Identification of Antibacterial Metabolites from Endophytic Fungus Aspergillus fumigatus, Isolated from Albizia lucidior Leaves (Fabaceae), Utilizing Metabolomic and Molecular Docking Techniques

et al. 2022

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“…Some of the common genera of endophytic bacteria that have been iso from plants include Bacillus [20][21][22][23][24], Pantoea [22,23], Streptomyces [25] and Enterobacter However, a greater percentage of biologically active compounds isolated from bac vary, with the genus Streptomyces being the most examined for the production of sp ized metabolites [13]. Similarly, a variety of endophytic fungi have been reported; com genera, among others, include Fusarium, Colletotrichum [27][28][29] and Phoma [29,30]. review aims to provide dynamic information about specialized metabolites from o isms.…”

Section: Introductionmentioning

confidence: 99%

Production and Functionalities of Specialized Metabolites from Different Organic Sources

et al. 2022

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Medicinal plants are rich sources of specialized metabolites that are of great importance to plants, animals, and humans. The usefulness of active biological compounds cuts across different fields, such as agriculture, forestry, food processing and packaging, biofuels, biocatalysts, and environmental remediation. In recent years, research has shifted toward the use of microbes, especially endophytes (bacteria, fungi, and viruses), and the combination of these organisms with other alternatives to optimize the production and regulation of these compounds. This review reinforces the production of specialized metabolites, especially by plants and microorganisms, and the effectiveness of microorganisms in increasing the production/concentration of these compounds in plants. The study also highlights the functions of these compounds in plants and their applications in various fields. New research areas that should be explored to produce and regulate these compounds, especially in plants and microbes, have been identified. Methods involving molecular studies are yet to be fully explored, and next-generation sequencing possesses an interesting and reliable approach.

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Novel Biological and Biotechnological Methods of Nematode Management, an Effective Strategy to Enhance Crop Productivity

d’Errico,

Silvia

2023

Novel Biological and Biotechnological Applications in Plant Nematode Management

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A Survey of Endophytic Fungi Associated with High-Risk Plants Imported for Ornamental Purposes

Cited by 10 publications

References 154 publications

Identification of Antibacterial Metabolites from Endophytic Fungus Aspergillus fumigatus, Isolated from Albizia lucidior Leaves (Fabaceae), Utilizing Metabolomic and Molecular Docking Techniques

Identification of Antibacterial Metabolites from Endophytic Fungus Aspergillus fumigatus, Isolated from Albizia lucidior Leaves (Fabaceae), Utilizing Metabolomic and Molecular Docking Techniques

Production and Functionalities of Specialized Metabolites from Different Organic Sources

Novel Biological and Biotechnological Methods of Nematode Management, an Effective Strategy to Enhance Crop Productivity

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