A Survey of Leptospiral Antibody of Dogs in Yamaguchi Prefecture

Shibanai, Daisuke; E, Ryu; Fukuda, Yuji; Ito, Reiko; Fujii, Takako; Hara, Yoshihiko; Abu, Masao; Hashimoto, M.; Fukuda, Nobuomi; Yamagata, J

doi:10.12935/jvma1951.27.753

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“…A MAT survey in 1999 using eight standard serovars (the 5 used in the present study plus the Pyrogenes, Pomona, and Hardjo strains) found prevalence rates of 25.8% in Hokkaido (16/62), 40.0% in Shizuoka (30/75), 8.9% in Toyama (9/101), 10.0% in Hyogo (13/130), 15.0% in Okayama (9/60), and 29.0% in Okinawa (18/62) [1]. An earlier MAT survey (conducted in 1989) using the same antigens found a prevalence rate of 23.5% in Kagoshima (190/806) [2], while a much earlier rapid MAT (RMAT) survey (conducted in 1974) using only the Icterohaemorrhagiae and Canicola strains found a prevalence rate of 15.2% in Yamaguchi (99/650) [17]. In the present study, taking into account the results obtained across all of the dogs examined (Fig.…”

Section: Discussionmentioning

confidence: 98%

“…There are a few reports of the prevalence of canine Leptospira antibodies in Japan [1,2,17]. A MAT survey in 1999 using eight standard serovars (the 5 used in the present study plus the Pyrogenes, Pomona, and Hardjo strains) found prevalence rates of 25.8% in Hokkaido (16/62), 40.0% in Shizuoka (30/75), 8.9% in Toyama (9/101), 10.0% in Hyogo (13/130), 15.0% in Okayama (9/60), and 29.0% in Okinawa (18/62) [1].…”

Section: Discussionmentioning

confidence: 99%

“…Clarifying the geographical distribution of dogs infected with L. interrogans is thus likely to be useful in terms of both clinical veterinary medicine and public health. In Japan, epidemiological surveys of leptospirosis have been conducted in rodents in Hokkaido, Shizuoka, Aichi, Miyazaki, and Okinawa [14], and in dogs in Hokkaido [1], Yamaguchi [17], and Kagoshima [2]. However, to the best of our knowledge there has been no nationwide survey on Leptospira infection in dogs.…”

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confidence: 99%

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Nationwide Survey of Leptospira Antibodies in Dogs in Japan: Results from Microscopic Agglutination Test and Enzyme-Linked Immunosorbent Assay

Iwamoto

Wada

Fujisaki

et al. 2009

The Journal of Veterinary Medical Science

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ABSTRACT. Leptospirosis is an infectious disease caused by Leptospira interrogans sensu lato and is common in both humans and animals. In the present study, serum samples were collected from 801 dogs across all 47 prefectures in Japan, and evaluated with a microscopic agglutination test (MAT), using 5 major L. interrogans serovars (Icterohaemorrhagiae, Canicola, Autumnalis, Hebdomadis, and Australis) as antigens, and an enzyme-linked immunosorbent assay (ELISA) using recombinant OmpL1 protein as the antigen. Across all dogs tested, 217 (27.0%) and 29 (3.6%) were MAT-and ELISA-positive, respectively. However, evidence strongly suggests that MAT also detected antibodies produced by vaccination. Of 243 dogs never inoculated with any canine vaccine, 41 (16.9%) from 23 prefectures were MAT and/or ELISA positive. The most commonly detected serovar was Icterohaemorrhagiae (22 dogs, 19 prefectures). Our results suggest that there are dogs with subclinical Leptospira infection throughout Japan. To the best of our knowledge, the present study is the first nationwide survey of Leptospira infection in dogs, and the findings are relevant not only for clinical veterinary medicine but also for public health.

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Section: Discussionmentioning

confidence: 98%