Objective: To explore responses from primary care physicians(PCPs) from an integrative physician (IP) consultation and recommended integrative oncology (IO) treatment program.Methods: Chemotherapy-treated patients were referred by their oncology healthcare professional to an IP, a physician dually-trained in complementary medicine and supportive cancer care. The consultation summary and patient-centered IO treatment program was then sent to the patient's PCP, with PCP-to-IP responses analyzed qualitatively using ATLAS.Ti software for systematic coding and content analysis. Trial Registration Number NCT01860365 published May 22, 2013. Results: Of the 597 IP consultations conducted, 470 (78.7%) summaries were sent to patients' PCPs, with only 69 (14.7%) PCP-to-IP responses returned. PCPs were more likely to respond if the patient was Hebrew-speaking (78.3% vs. 65.1%, P=0.032). Systematic coding identi ed four predominant themes among PCP narratives: addressing the patient's medical condition and leading QoL-related concerns; patient-centered re ections; available resources providing support and promoting resilience; and PCP attitudes to the IO treatment program.Conclusion: PCP-IP communication can provide valuable insight into the patient's bio-psycho-social care, addressing the patient's health-belief model, emotional concerns, caregiver-related factors, preferences and barriers to adherence to IO care. Practice implications: Healthcare services should consider promoting IP-PCP communication in order to facilitate better patient outcomes from an IO treatment program. present a number of challenges vis-à-vis patient-doctor-CIM practitioner communication. Patients also perceive physician-CIM practitioner communication as important and instrumental in promoting health, effective treatment and safety[12, 13]. Schiff et al compared the perspectives of 473 physicians and 781CIM practitioners in Israel, and suggested a practical framework agreed upon by both for advancing a physician-CIM practitioner dialogue which is based on referral letters that include four elements: medical diagnosis; establishing treatment goals; addressing safety-related issues; and quality of care-related concerns [14]. In another Israeli study focusing on PCPs and CIM practitioners' perspectives regarding a clinical practice collaboration, the majority of participants in both groups preferred using a written medical letter to communicate with each other, with the goal of co-structuring a treatment plan for their patients [15]. In contrast to non-medical CIM practitioners, physicians trained in both conventional and complementary medicine were found to prefer a referral letter to advance doctor-CIM practitioner communication [16].The present study explored the communication between integrative physicians (IPs), medical doctors with dual training in CIM and supportive/palliative care. The study setting is unique, in which an initial IP consultation is provided without charge to patients as part of the medical center's supportive and palliative car...