A Survey of Tuberculin and Histoplasmin Reactors Among School Children of Washtenaw County, Mich

Abstract

A4dministration of tuberculin and histoplasmin skin tests revealed the existence of an area in southeastern Michigan with an unusually large number of individuals with past experience with histoplasmosis. This project was conducted jointly by public and voluntary health agencies.

Histoplasmosis in a pediatric oncology center

“…Most patients with cancer and acute histoplasmosis in this study were male, although this proportion was not statistically different from the proportion in the population of patients with cancer cared for during the study period (P = .190; expected number of boys among 33 patients, [13][14][15][16][17][18][19][20][21][22][23][24][25]. A similar preponderance of male patients has been found by serosurveys of healthy children and those undergoing evaluation for mediastinal masses.…”

“…A similar preponderance of male patients has been found by serosurveys of healthy children and those undergoing evaluation for mediastinal masses. 15,16 This sex distribution may reflect an increased susceptibility to disease, likelihood of severe disease, or exposure to environmental sources of histoplasmosis.…”

Airborne Histoplasmosis

“…In Milan, Mich., another endemic area has been reported where the sensitivity rate in the city is over 60 %, compared to 2 to 11% in the surrounding country (4). Here, starlings were present in such abundance that city sidewalks were white with droppings.…”