A survey on mortality from non-variceal upper gastrointestinal bleeding: Is the emergency referral system adequate?

Cesaro, Paola; Kohn, Anna; Petruziello, Lucio; Angélico, M.; Franceschi, Francesco; Gigliozzi, Alessandro; Lamazza, Antonietta; Tammaro, Leonardo; Boschetto, S.; Brighi, Stefano; Antoniozzi, Angelo; Baiocchi, Leonardo

doi:10.1016/j.dld.2013.04.010

Cited by 6 publications

(2 citation statements)

References 17 publications

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“…The optimal cut-off value to predict mortality was determined using the Youden index method, which defines the cut-off in terms of the maximal sum of sensitivity and specificity. Survival analysis was conducted using the Kaplan Meier test and statistical differences were evaluated using the log-rank test as previously described [23]. All statistical analyses were conducted using the Statistical Software Package NCSS (Kaysville, UT).…”

Section: Methodsmentioning

confidence: 99%

Relationship between GH/IGF-1 Axis, Graft Recovery, and Early Survival in Patients Undergoing Liver Transplantation

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Tariciotti

et al. 2014

BioMed Research International

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Background. High levels of IGF-1 have been reported in patients with initial poor function of the graft after liver transplantation (LT). Correlation with other clinical variables or early survival has not been extensively investigated. Aim. To evaluate the GH/IGF-1 profile as a function of liver recovery and patients' early survival after LT. Methods. 30 transplanted patients (23 survivors and 7 nonsurvivors), were retrospectively enrolled in the study. GH and IGF-1 serum levels were assessed at baseline, graft reperfusion, and 1, 7, 15, 30 , 90, and 360 days after LT. Individual biochemical variables were also recorded. Results. After grafting, IGF-1 in blood linearly correlated with cholesterol (r = 0.6, P = 0.001). IGF-1 levels from day 15 after surgery were statistically higher in survivors as compared to nonsurvivors. ROC curves analysis identified an IGF-1 cut-off >90 μg/L, from day 15 after surgery, as a good predictor of survival (sensitivity 86%, specificity 95%, and P < 0.001). Conclusions. After LT, GH levels correlate with the extent of cytolysis, while IGF-1 is an indicator of liver synthetic function recovery. IGF-1 levels >90 μg/L (day 15–30) seem to be an indicator of short-term survival.

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Section: Methodsmentioning

confidence: 99%

Relationship between GH/IGF-1 Axis, Graft Recovery, and Early Survival in Patients Undergoing Liver Transplantation

Salso

Tisone

Tariciotti

et al. 2014

BioMed Research International

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“…Organization of the emergency referral system was also the subject of a retrospective survey conducted by the regional sections of the three main Italian gastroenterological societies, AIGO, SIED and SIGE, evaluating all consecutive episodes of non-variceal upper gastrointestinal bleeding referred to sevencenters (four of which were Level-II Emergency Departments) in Rome, Italy, during a oneyear period [25]. A total of 624 consecutive patients (64% males, mean age 67.6 ± 16.2 years) were included.…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%