This paper points out the shortcomings of existing normalization methods, and proposes a brightness temperature inversion normalization method for multi-source remote sensing monitoring of forest fires. This method can satisfy both radiation normalization and observation angle normalization, and reduce the discrepancies in forest fire monitoring between multi-source sensors. The study was based on Himawari-8 data; the longitude, latitude, solar zenith angle, solar azimuth angle, emissivity, slope, aspect, elevation, and brightness temperature values were collected as modeling parameters. The mixed-effects brightness temperature inversion normalization (MEMN) model based on FY-4A and Himawari-8 satellite sensors is fitted by multiple stepwise regression and mixed-effects modeling methods. The results show that, when the model is tested by Himawari-8 data, the coefficient of determination (R2) reaches 0.8418, and when it is tested by FY-4A data, R2 reaches 0.8045. At the same time, through comparison and analysis, the accuracy of the MEMN method is higher than that of the random forest normalization method (RF) (R2=0.7318), the pseudo-invariant feature method (PIF) (R2=0.7264), and the automatic control scatter regression method (ASCR) (R2=0.6841). The MEMN model can not only reduce the discrepancies in forest fire monitoring owing to different satellite sensors between FY-4A and Himawari-8, but also improve the accuracy and timeliness of forest fire monitoring.