A Sustainable Ruthenium(III) Chloride Catalyzed Alcohol Oxidation

Abstract

Systematic optimization of the ruthenium‐catalyzed oxid­ation of alcohols with tert‐butyl hydroperoxide (TBHP) as the oxidizing agent was carried out. This resulted in the development of a sustain­able protocol with a water/tert‐butanol mixture as the solvent and an optimum use of the oxidizing agent by continuous addition with a syringe pump. The protocol is applicable for a broad variety of substrates. High yields of ketones and aldehydes are accessible.