A synthetic ditryptophan conjugate that rescues bacteria from mercury toxicity through complexation

Peptide-based Synthetic Design, Construction and Morphology of Soft Structures

“…5). [23] Thus, it is possible to design soft structures with suitable metal ion-responsive linkers for biological applications.…”

“…Conjugate 4 afforded formation of spherical structures in solution. [23] It is important to emphasize that dipeptide alone did not give stable structures in solution despite long incubation periods. Interestingly, 4 also exhibited selective interaction toward Hg 2+ ions as determined by competitive titration experiments conducted with various metal ions.…”

Mercury-instructed assembly (MiA): architecting clathrin triskelion-inspired highly functional C3-symmetric triskelion nanotorus functional structures into microtorus structures

“…21,24 Alternatively, the use of microscopy tools such as force and electron microscopy have widely been used to investigate the morphological changes in molecule of interests occurring in the presence of various analytes. 21,24,30…”

Novel Pentadecyl Phenol‐Tagged L‐Tryptophan Molecules: Synthesis, Self‐ Assembly and Liquid Crystalline Properties

“…Tryptophan based soft nanostructures have already been explored by Verma and co‐workers , The aromatic moieties in Trp offers π‐π interactions for effective stabilization of self‐assembled structures . Trp is a hydrophobic fluorescent amino acid which undergoes π‐π interactions and eventually form tryptophan zippers ,.…”

“…The fluorescent property of Trp can be utilized in analysing the self assembly. Ditryptophan‐pyridine conjugates could act as fluorescent probes for selective binding of Hg ions . Amphiphilic ditryptophan conjugates were used for synthesizing gold nanoparticles and tryptophan based peptidic proton sensors and drug delivery vehicles containing tryptophan were also developed and studied ,…”