A Synthetic Porous Ceramic as a Bone Graft Substitute in the Surgical Management of Scoliosis

Abstract

These results justify and favor the use of calcium phosphate ceramics as bone graft substitutes for instrumented posterior spinal fusion in teenagers and young adults. Potentially hazardous harvesting of pelvic bone is no longer necessary for such operations.

Correlative radiological, self-assessment and clinical analysis of evolution in instrumented dorsal and lateral fusion for degenerative lumbar spine disease. Autograft versus coralline hydroxyapatite

“…Delecrin et al [19] in a clinical study compared two groups of adolescent and young adult patients who were operated posteriorly for idiopathic scoliosis autogenous and received CD instrumentation supplemented with either autologous IBG or porous biphasic calcium phosphate ceramic blocks, comprising HA and tricalcium phosphate mixed with local bone chips. These authors showed that the patients who received ceramics had lower blood loss were free from postoperative local complications, while radiographically there was demonstrated successful incorporation of the ceramic blocks within 1 year.…”

Use of hydroxyapatite in spine surgery

“…In applying their results of animal studies to clinical practice, Delecrin et al, in a prospective randomized study, assessed the clinical and radiologic performances of a synthetic ceramic as a bone graft substitute in scoliosis surgery [10]. Fifty-eight patients with idiopathic scoliosis underwent posterior correction and arthrodesis by posterior spinal fusion using autogenous iliac bone grafts alone or in combination with porous biphasic calcium phosphate ceramic blocks comprised of HA/TCP.…”

Substitutos ósseos comparados ao enxerto ósseo autólogo em cirurgia ortopédica: revisão sistemática da literatura

“…A synthetic porous ceramic as a bone graft substitute in the surgical management of Delecrin et al (23) scoliosis: a prospective, randomized study.…”

“…envolvendo BMP-2 (5)(6)9,15,17,(20)(21) , três utilizando BMP-7 (10)(11)19) , sete envolvendo biocerâmicas, como hidroxiapatita, fosfato tricálcio e sulfato de cálcio (12)(13)(14)16,18,(22)(23) . O substituto ósseo mostrou-se equivalente ao enxerto autólogo em 19 estudos (4)(5)(6)(7)(8)(9)(10)(11)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23) e inferior em três (12,(24)(25) .…”

“…O substituto ósseo mostrou-se equivalente ao enxerto autólogo em 19 estudos (4)(5)(6)(7)(8)(9)(10)(11)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23) e inferior em três (12,(24)(25) .…”