A systematic literature review of quality of life in lower limb amputees

Sinha, Richa; Heuvel, W.J.A. van den

doi:10.3109/09638288.2010.514646

Cited by 124 publications

(122 citation statements)

References 38 publications

Supporting

Mentioning

102

Contrasting

Unclassified

Order By: Relevance

“…This contrasts with previous studies of QoL (13) and other psychosocial outcomes (1, 40) among people with LLA, in which males have tended to perform more favourably when gender differences are observed. Age was also significantly predictive of environmental QoL, with older individuals having higher scores at 6-month follow-up.…”

Section: Discussioncontrasting

confidence: 99%

“…Measures of QoL provide insight into the subjective experience of illness and disability, taking into account a broad range of areas including perceived health and physical functioning, social relationships, psychological well-being, and environmental support, and their inclusion in routine clinical assessment following amputation has been recommended (12). QoL is a complex issue, however, and research in this patient group has been hampered by methodological issues including heterogeneity of samples and measurement tools, and a surplus of cross-sectional designs (13,14). Further longitudinal studies of QoL to examine changes in this outcome over time and assess its determinants among individuals with amputations are required.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Goal Pursuit and Goal Adjustment as Predictors of Disability and Quality of Life Among Individuals With a Lower Limb Amputation: A Prospective Study

Coffey

Desmond

2014

Archives of Physical Medicine and Rehabilitation

View full text Add to dashboard Cite

Objective: (1) To identify significant changes in disability and quality of life (QoL) across three time points (T1 = admission to rehabilitation, T2 = six weeks post-discharge, T3 = six months post-discharge) in individuals with lower limb amputation, and (2) to examine whether goal pursuit and goal adjustment at T1 were predictive of these outcomes at T3.Design: Prospective cohort study. Setting: Inpatient rehabilitation.Participants: Consecutive sample of 64 persons aged 18 years and over with major lower limb amputation.Interventions: Not applicable. Main Outcome Measures: World Health Organisation Disability Assessment ScheduleVersion 2.0 (WHODAS 2.0); World Health Organisation Quality of Life Questionnaire-Brief Version (WHOQOL-BREF).Results: Mean WHODAS 2.0 scores were in the 95 th percentile at each time point. Scores on the WHODAS 2.0 and the physical, psychological and social relationships domains of the WHOQOL-BREF remained stable across the study period. Environmental QoL scores decreased from T1 to T2, but returned to near-baseline levels between T2 and T3. Having a greater tendency towards goal pursuit at T1 was predictive of higher physical and psychological QoL at T3, while having a stronger disposition towards goal adjustment at T1 predicted lower disability and higher environmental QoL at T3. Conclusions:High levels of disability were experienced from admission to rehabilitation up to six months post-discharge. QoL in the physical, psychological and social relationships domains remained stable over the study period. Stronger goal pursuit and goal adjustment 3 tendencies on admission predicted lower disability and higher QoL six months postdischarge. and health classification system that offers a generic framework for describing the consequences of illness and disability and the dynamic interplay of personal and environmental factors (5), and has been applied to a number of conditions, including LLA (5, 6). The ICF classifies functioning and disability into two components: (1) body functions and structures (at the level of the body or body part), which are interpreted through changes in physiological systems or anatomical structures; and (2) activities (at the level of the whole person) and participation (at the level of the whole person in a social context), which are interpreted through capacity and performance.The primary goal of rehabilitation is to achieve optimal functioning (as appropriate to the individual) at each of these levels (7). Recent reviews indicate that most rehabilitation outcomes research among persons with LLA has been at the level of body functions and structures (2) or specific activities such as mobility (6) Theories of self-regulation may help to increase understanding of adjustment to LLA (17, 18). According to this perspective, human behaviour is organised around the pursuit of goals, which energise activities and give structure and meaning to people's lives and are thus closely linked with their subjective well-being (19-21). Indeed, negative associations hav...

show abstract

Section: Discussioncontrasting

confidence: 99%

mentioning

confidence: 99%

Goal Pursuit and Goal Adjustment as Predictors of Disability and Quality of Life Among Individuals With a Lower Limb Amputation: A Prospective Study

Coffey

Desmond

2014

Archives of Physical Medicine and Rehabilitation

View full text Add to dashboard Cite

show abstract

“…Although a profile of lower-limb amputee QOL and falls efficacy has been presented, the literature points to a paucity of longitudinal studies in this area of research [14]. Understanding the changes that occur in QOL and falls efficacy over time following discharge from rehabilitation is important for this population.…”

Section: Introductionmentioning

confidence: 99%

“…Reports of QOL have varied, with people with lowerlimb amputation being equal to or higher [11][12] and lower [8][9][10][13][14] than normative reference data, indicating that no general consensus exists on how amputation affects QOL. However, a higher level of amputation (e.g., transfemoral vs transtibial) has been associated with decreased QOL [15].…”

Section: Introductionmentioning

confidence: 99%

“…Factors affecting mental health include depression, which is considered an important predictor of QOL [11], as well as the aesthetics of the prosthesis [13,16] and employment status [8]. Studies have also shown QOL to be highly related to both the physical [13][14] and social [19] aspects of an amputee's life, as well as being closely associated to the functioning of his or her prosthesis [8,[12][13].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Temporal adaptations in generic and population-specific quality of life and falls efficacy in men with recent lower-limb amputations

Barnett¹,

Vanicek²,

Polman³

2013

JRRD

View full text Add to dashboard Cite

Abstract-This study examined the longitudinal changes in generic health-related quality of life (QOL), prosthesis-related QOL, falls efficacy, and walking speed in men with lower-limb amputations up to 6 months following discharge from rehabilitation. Seven male unilateral transtibial amputees completed the Medical Outcomes Study 36-Item Short Form Health Survey, the Prosthesis Evaluation Questionnaire, and the Modified Falls Efficacy Scale at 1, 3, and 6 months postdischarge from rehabilitation. Walking speed was also recorded to objectively assess participants' mobility. Health-related QOL measures displayed increases, resulting in large effect sizes though not reaching statistical significance. Prosthesis-related QOL measures indicated that scales relating to the participants' prostheses improved and the support of significant others was the most positively scored variable. Walking speed increased by 0.12 m/ s, although it was not significantly related to indices of QOL or falls efficacy. Falls efficacy did not improve significantly during the study period, although it was strongly related to QOL (p < 0.05). These results provide a novel insight into how QOL and falls efficacy develop in people with lower-limb amputations, alongside changes in mobility, after discharge from rehabilitation. Further improvements in physical health following discharge may be required to elicit subsequent increases in overall QOL and concurrent improvements in falls efficacy.

show abstract

Pharmacologic interventions for treating phantom limb pain

Alviar

Hale

Dungca³

2016

Cochrane Database of Systematic Reviews

138

View full text Add to dashboard Cite

Since the last version of this review, we identified another study that added another form of medical therapy, BoNTs, specifically BoNT/A, to the list of pharmacologic interventions being reviewed for clinical efficacy in phantom limb pain. However, the results of this study did not substantially change the main conclusions. The short- and long-term effectiveness of BoNT/A, opioids, NMDA receptor antagonists, anticonvulsants, antidepressants, calcitonins, and local anaesthetics for clinically relevant outcomes including pain, function, mood, sleep, quality of life, treatment satisfaction, and adverse events remain unclear. Based on a small study, BoNT/A (versus lidocaine/methylprednisolone) does not decrease phantom limb pain. Morphine, gabapentin, and ketamine demonstrate favourable short-term analgesic efficacy compared with placebo. Memantine and amitriptyline may not be effective for PLP. However, results must be interpreted with caution, as they were based mostly on a small number of studies with limited sample sizes that varied considerably and also lacked long-term efficacy and safety outcomes. The direction of efficacy of calcitonin, local anaesthetics, and dextromethorphan needs further clarification. Overall, the efficacy evidence for the reviewed medications is thus far inconclusive. Larger and more rigorous randomised controlled trials are needed for us to reach more definitive conclusions about which medications would be useful for clinical practice.

show abstract

A systematic literature review of quality of life in lower limb amputees

Cited by 124 publications

References 38 publications

Goal Pursuit and Goal Adjustment as Predictors of Disability and Quality of Life Among Individuals With a Lower Limb Amputation: A Prospective Study

Goal Pursuit and Goal Adjustment as Predictors of Disability and Quality of Life Among Individuals With a Lower Limb Amputation: A Prospective Study

Temporal adaptations in generic and population-specific quality of life and falls efficacy in men with recent lower-limb amputations

Pharmacologic interventions for treating phantom limb pain

Contact Info

Product

Resources

About