A systematic literature review on solitary rectal ulcer syndrome: is there a therapeutic consensus in 2018?

Abstract

The general quality of the studies focusing on the treatment of SRUS was poor due to the heterogeneity of the population, the sample size of the cohorts, and the heterogeneity of efficacy assessments. The therapeutic approach appears to be multimodal and multidisciplinary and validated in centres of expertise. Further studies evaluating multimodal strategies are needed.

The Long-term Efficacy of Endoscopic Submucosal Dissection in the Treatment of Symptomatic Mucosal Prolapse Syndrome

“…In the present case, we were able to successfully remove the MPS lesion and control the bleeding by ESD, thus improving the symptoms without any intraoperative or postoperative complications. Conservative treatment is the first-line therapy for symptomatic MPS and SRUS (11,12). This includes laxatives with a high-fiber diet, a change in defecatory habits, and the use of biofeedback.…”

“…This includes laxatives with a high-fiber diet, a change in defecatory habits, and the use of biofeedback. Improvement is seen in 63.6% of patients (11). Topical therapy and surgery are considered when conservative treatment fails.…”

“…Biofeedback improved MPS and SRUS in 62% (36-75%) of patients (5-7); of these, 50% experienced recurrence at a median observation period of 36 months (5). Surgery improved MPS and SRUS in 77% (54-100%) of the patients; of these, 52% (25-100%) experienced recurrence (11). The long-term efficacy of topical therapy is unknown (13)(14)(15)(16)(17)(18)(19).…”

Modified Tong Xie Yao Fang relieves solitary rectal ulcer syndrome: A case report

“…Probiotics may also have preventive effects on colorectal cancer but the actual beneficial effects remain to be definitively evidenced[7,8]. Conservative treatment (high-fiber diet, laxatives, change in defecatory habits, and biofeedback treatment) were shown to induce a symptomatic improvement in 71/91 patients (63.6%) and healing of mucosal lesion in 17/51 patients (33.3%)[9]. According to those reports, SRUS may be prevented and improved by adjusting dietary structures and probiotic levels.…”

Proktitis (ohne chronisch-entzündliche Darmerkrankung)

“…Ursächlich können hier Stuhlimpaktionen oder Fremdkörper (unter anderem Vibratoren, Pessare) oder wiederkehrende Scherkräfte wie bei Intussuszeption (Ulcus simplex recti) oder Rektumprolaps dritten Grades und sogar Hämorrhoidalprolaps lokalen Druck auf das Rektum ausüben und damit lokale Ischämien und Entzündungen bzw. Ulzera verursachen [35,36,37]. Bei länger bestehenden Scherkräften, etwa bei Intussuszeption, können auch derbe, polypoide, tastbare Gebilde entstehen, die mittels Biopsie von einem neoplastischen Geschehen unterschieden werden können.…”