A Systematic Requirement Analysis for Dynamic Pricing in Retail E-Commerce

Kumari, Archana; Kumar, S. Mohan; K, Babu Rao

doi:10.22214/ijraset.2023.49418

Cited by 1 publication

(1 citation statement)

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“…RasMol is an early molecular visualization software tool that has been widely used in the field of structural biology and biochemistry. It was first developed in the early 1990s by Roger Sayle and has been instrumental in the exploration of protein and nucleic acid structures [15,16]. PyMOL is a more modern and versatile molecular visualization tool that has gained popularity in the field of structural biology.…”

Section: Methodsmentioning

confidence: 99%

Homology Modeling and Structure Based Drug Design for Human Gastric Cancer

Kumari,

Bora,

Akshaya

2023

IJRASET

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This research article delves into the multifaceted world of structural biology and bioinformatics, exploring a diverse array of tools and resources employed to decipher the intricacies of proteins and their implications in health and disease. The paper navigates through various computational tools and databases used for sequence analysis, structural analysis, mutation site detection, and molecular docking, shedding light on their individual contributions in unraveling the secrets of proteins. COBALT serves as the initial compass, guiding researchers in the alignment of protein sequences, identifying conserved domains, and elucidating structural features in proteins. The exploration continues, with a focus on tools such as RasMol, PyMol, and Pharmit. This research article explores a range of bioinformatics tools and databases crucial for elucidating the complex world of proteins and their involvement in diseases like gastric cancer. It begins by highlighting the pivotal role of the Catalogue of Somatic Mutations in Cancer (COSMIC) in mutation site detection, providing a comprehensive repository of somatic mutations in cancer. The Kyoto Encyclopedia of Genes and Genomes (KEGG) complements this with a wealth of biological data and pathways. Shifting the focus to protein stability and dynamics, the article introduces DynaMUT, a computational tool employing molecular dynamics simulations to predict mutation impacts on protein behavior. Lastly, SwissDock takes the stage for drug discovery, facilitating the prediction and analysis of interactions between small molecules and target proteins. Collectively, these tools and databases offer an interdisciplinary lens through which researchers unravel protein intricacies and their relevance in diseases, exemplifying the indispensable role of structural biology and bioinformatics in advancing biological understanding.

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Section: Methodsmentioning

confidence: 99%