A Systematic Review and Meta-Analysis of Current Evidence Comparing Laparoendoscopic Single-Site Adrenalectomy and Conventional Laparoscopic Adrenalectomy

Hu, Qingfeng; Gou, Yuancheng; Sun, Chuanyu; Xu, Ke; Xia, Guowei; Ding, Qiang

doi:10.1089/end.2012.0687

Cited by 25 publications

(26 citation statements)

References 28 publications

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“…Similar outcomes and shorter hospital stay have been proven in retroperitoneoscopic adrenalectomy compared with traditional laparoscopic surgery [13–15]. In addition, the safeties and efficiencies of robot-assisted and laparoscopic single-site adrenalectomy compared to conventional laparoscopic surgery have demonstrated insignificant differences by systematic review and meta-analysis, respectively [16–18]. …”

Section: Discussionmentioning

confidence: 75%

Diagnosis and Treatment of Adrenal Medullary Hyperplasia: Experience from 12 Cases

Yang

Gao

et al. 2014

International Journal of Endocrinology

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Objective. To dissect the characteristics of adrenal medullary hyperplasia (AMH) and share our experience of diagnosis and treatment of AMH. Methods. From 1999 to 2013, 12 cases of AMH have been pathologically diagnosed after operation in our hospital. The clinical characteristics, process of diagnosis, treatment, and prognosis during follow-up of all patients are summarized retrospectively. Results. Four cases were trended to be AMH and 6 cases were trended to be pheochromocytoma before operation; moreover, the other two patients were diagnosed accidentally. All patients, except for the patient with mucinous tubular and spindle cell carcinoma of left kidney by open surgery, experienced a smooth laparoscopic adrenalectomy, including 2 with radical nephrectomy, 10 of which experienced unilateral adrenalectomy, 1 was bilaterally partial adrenalectomy, and the remaining one was unilaterally complete removal and then 2/3 partially contralateral excision. After a medium follow-up of 6.5 years, it demonstrated a satisfactory outcome of 8 cured patients and 4 symptomatic improved patients. Conclusions. AMH presents a mimicking morphology and clinical manifestation with pheochromocytoma. Surgery could be the only effective choice for the treatment of AMH and showed a preferable prognosis after a quite long follow-up.

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Section: Discussionmentioning

confidence: 75%

Diagnosis and Treatment of Adrenal Medullary Hyperplasia: Experience from 12 Cases

Yang

Gao

et al. 2014

International Journal of Endocrinology

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“…Meta-analysis comparing LESS adrenalectomy versus conventional laparoscopic surgery showed no significant difference in estimated blood loss, time to oral intake resumption, complications, conversion and transfusion rates between the 2 groups [45464748]. However, patients who have undergone LESS adrenalectomy have a significantly lower postoperative visual analog pain score [46] or had less analgesia demand [47].…”

Section: Less Adrenalectomymentioning

confidence: 99%

Robotic assisted adrenalectomy: Is it ready for prime time?

Teo

Lim

2016

Investig Clin Urol

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Adrenal surgery is undergoing continuous evolution and minimally invasive surgery is increasingly being used for the surgical management of adrenal masses. With robotic-assisted surgery being a widely accepted surgical treatment for many urological conditions such as prostate carcinoma and renal cell carcinoma, the use of the robot has been expanded to include robotic-assisted adrenalectomy, offering an alternative minimally invasive platform for adrenal surgery. We performed a literature review on robotic-assisted adrenalectomy, reviewing the current surgical techniques and perioperative outcomes.

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“…There are only two meta-analyses that have compared LESS and conventional laparoscopic adrenalectomy for benign adrenal lesions thus far [14, 15]. These studies revealed comparable incidence of procedure related adverse events (complication and conversion) between the two techniques.…”

Section: Discussionmentioning

confidence: 99%

“…A recent revolution in surgery, the endoscopic single-port surgery or laparoscopic single-site surgery (LESS), has been implemented in various surgical indications including adrenalectomy [6–13]. The preliminary results have revealed its superiority in aesthetics, postoperative pain, and convalescence [14, 15]. …”

Section: Introductionmentioning

confidence: 99%

Is Laparoendoscopic Single-Site Adrenalectomy a Feasible Alternative in Treating Aldosterone-Producing Adenoma?

et al. 2016

BioMed Research International

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Objective. To compare laparoendoscopic single-site (LESS) and conventional multiport adrenalectomy in patients with aldosterone-producing adenoma (APA). Material and Methods. We retrospectively reviewed patients who had been clinically confirmed with unilateral APA and who underwent LESS or multiport adrenalectomy between 2009 and 2014. Perioperative data were obtained for all patients. Blood pressure and the levels of serum aldosterone, renin, and potassium were checked periodically. Results. We identified 45 APA patients in the LESS group and 71 in the multiport group. The baseline characteristics were matched between two groups. All adrenalectomies were completed successfully, except one with laparoscopic conversion in the single-port group and one open conversion in the multiport group. After a mean follow-up around one year, there were no significant group differences in the improvement of hypertension, number of types of medication taken, and cure of hypokalemia after operation. Conclusions. Our study confirm that LESS adrenalectomy achieved similar clinical and functional outcomes as conventional multiport adrenalectomy for management of unilateral APA.

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A Systematic Review and Meta-Analysis of Current Evidence Comparing Laparoendoscopic Single-Site Adrenalectomy and Conventional Laparoscopic Adrenalectomy

Abstract: Based on current evidence, the operative time seems to be longer in LESS-A; however, operative blood loss and complications are similar. In addition, LESS-A presents a shorter hospital stay after surgery and more acceptable perception of pain than conventional LA.

Cited by 25 publications

References 28 publications

Diagnosis and Treatment of Adrenal Medullary Hyperplasia: Experience from 12 Cases

Diagnosis and Treatment of Adrenal Medullary Hyperplasia: Experience from 12 Cases

Robotic assisted adrenalectomy: Is it ready for prime time?

Is Laparoendoscopic Single-Site Adrenalectomy a Feasible Alternative in Treating Aldosterone-Producing Adenoma?

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