A systematic review and meta‐analysis of the mental health symptoms during the <scp>Covid‐19</scp> pandemic in <scp>S</scp>outheast <scp>A</scp>sia

Pappa, Sofia; Chen, Jiyao; Barnett, Joshua; Chang, Anabel; Dong, Rebecca Kechen; Xu, Wen; Yin, Allen; Chen, Bryan Z.; Delios, Andrew; Chen, Richard Z.; Miller, Saylor; Wan, Xue; Zhang, Stephen X.

doi:10.1111/pcn.13306

Cited by 52 publications

(23 citation statements)

References 77 publications

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“…Explanatory factors of the high heterogeneity and moderators were roughly similar to those in the general population such as different scales and cutoffs (e.g., [ 33 ]), non-random sampling or sample (size) differences (e.g., [ 34 , 36 ]), region of study (e.g., [ 74 , 135 ]), and quality or risk of bias scores of studies [ 9 , 42 ]. Similarly, prevalence rates were higher in studies with larger proportions of female versus male workers, medical versus non-medical professionals, frontline versus non-frontline workers, and nurses versus doctors (e.g., [ 27 , 41 , 56 , 97 , 102 , 105 , 107 , 123 ]). Prevalence rates of above cut-off PTSD level were related to COVID-19 mortality rate [ 60 ] and inconsistently to age (e.g., higher in older [ 61 , 143 ] or in younger health professionals [ 138 ]).…”

Section: Resultsmentioning

confidence: 99%

COVID-19 and common mental health symptoms in the early phase of the pandemic: An umbrella review of the evidence

et al. 2023

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Background There remains uncertainty about the impact of the Coronavirus Disease 2019 (COVID-19) pandemic on mental health. This umbrella review provides a comprehensive overview of the association between the pandemic and common mental disorders. We qualitatively summarized evidence from reviews with meta-analyses of individual study-data in the general population, healthcare workers, and specific at-risk populations. Methods and findings A systematic search was carried out in 5 databases for peer-reviewed systematic reviews with meta-analyses of prevalence of depression, anxiety, and post-traumatic stress disorder (PTSD) symptoms during the pandemic published between December 31, 2019 until August 12, 2022. We identified 123 reviews of which 7 provided standardized mean differences (SMDs) either from longitudinal pre- to during pandemic study-data or from cross-sectional study-data compared to matched pre-pandemic data. Methodological quality rated with the Assessment of Multiple Systematic Reviews checklist scores (AMSTAR 2) instrument was generally low to moderate. Small but significant increases of depression, anxiety, and/or general mental health symptoms were reported in the general population, in people with preexisting physical health conditions, and in children (3 reviews; SMDs ranged from 0.11 to 0.28). Mental health and depression symptoms significantly increased during periods of social restrictions (1 review; SMDs of 0.41 and 0.83, respectively) but anxiety symptoms did not (SMD: 0.26). Increases of depression symptoms were generally larger and longer-lasting during the pandemic (3 reviews; SMDs depression ranged from 0.16 to 0.23) than those of anxiety (2 reviews: SMDs 0.12 and 0.18). Females showed a significantly larger increase in anxiety symptoms than males (1 review: SMD 0.15). In healthcare workers, people with preexisting mental disorders, any patient group, children and adolescents, and in students, no significant differences from pre- to during pandemic were found (2 reviews; SMD’s ranging from −0.16 to 0.48). In 116 reviews pooled cross-sectional prevalence rates of depression, anxiety, and PTSD symptoms ranged from 9% to 48% across populations. Although heterogeneity between studies was high and largely unexplained, assessment tools and cut-offs used, age, sex or gender, and COVID-19 exposure factors were found to be moderators in some reviews. The major limitations are the inability to quantify and explain the high heterogeneity across reviews included and the shortage of within-person data from multiple longitudinal studies. Conclusions A small but consistent deterioration of mental health and particularly depression during early pandemic and during social restrictions has been found in the general population and in people with chronic somatic disorders. Also, associations between mental health and the pandemic were stronger in females and younger age groups than in others. Explanatory individual-level, COVID-19 exposure, and time-course factors were scarce and showed inconsistencies across reviews. For policy and research, repeated assessments of mental health in population panels including vulnerable individuals are recommended to respond to current and future health crises.

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Section: Resultsmentioning

confidence: 99%

COVID-19 and common mental health symptoms in the early phase of the pandemic: An umbrella review of the evidence

et al. 2023

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“…The incidence of depression, anxiety and sleep disorders were 36, 34, and 52%, respectively in Spanish medical personnel (37); 37, 23, and 34% in Latin America (38); 55, 51, and 28% in Africa (39); 34%, 46% (40), and 40% (41) in Eastern Europe. And the prevalence of depression, anxiety and sleep disorders among health-care workers in south-east Asia were generally lower than other regions during the pandemic, which were 14, 23, and 18% (42), respectively. Therefore, the prevalence of mental health symptoms during the COVID-19 pandemic is not homogeneous across different regions.…”

Section: Discussionmentioning

confidence: 90%

Psychological status of medical staff dedicated to nucleic acid collection in COVID-19 epidemic during closed-loop management: A cross-sectional study

Sun

Yao

et al. 2023

Front. Public Health

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BackgroundTo investigate the depression, anxiety and somnipathy situation occurred in the nucleic acid collection staff during the closed-loop management period of COVID-19. And try to understand the influencing factors of related psychological status.MethodsA cross-sectional study of 1,014 nucleic acid collection staff from seven Chinese hospitals was conducted. Various investigation methods were involved in the questionnaires to collect data, including 12-items self-made questionnaire survey of basic demographic information, 9-items patient health questionnaire depression scale (PHQ-9), 7-items generalized anxiety disorder scale (GAD-7) and Pittsburgh sleep quality index (PSQI). Data analysis was performed using SPSS version 26.0 and Excel software. Mann-Whitney U-test, Chi-square test, correlation analysis, mono-factor analysis and binary logistic regression were applied accordingly for further analysis.ResultsThe positive rate of depression, anxiety and sleep disorder of 1,014 nucleic acid collectors under closed-loop management were 33.5, 27.2, and 50.1%, respectively. Depression was significantly positively correlated with anxiety and sleep (P < 0.05). The scores of depression scale were positively correlated with the age and the fear for infection (r = 0.106, 0.218, both P < 0.05); The scores of anxiety scale were also positively correlated with the age and the fear for infection (r = 0.124, 0.225, both P < 0.05); The length of service, collection time and the degree of worry about infection and was positively correlated with the score of sleep scale (r = 0.077, 0.074, 0.195, both P < 0.05); Education level had a significant negative association with PHQ-9, GAD-7 and PSQI (r = −0.167,−0.172, both P < 0.05). Binary logistic regression analysis showed that age, technical title, education level, collection time, collection frequency, collection location, fear for infection and external environment were important influencing factors of depression, anxiety and sleep disorders.ConclusionThe results of this study suggested that when carrying out nucleic acid collection mission, managers should intervene to optimize the collection location, control the duration of each collection mission, replace the collection staff in time and pay close attention to the psychological state of the collection staff.

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“…Another recent study (n = 155) reported 35.6% moderate to severe depressive symptoms during the COVID pandemic in Kosovo [8]. This is well above the mean found in Southeast Asia (16%) [9] but still below the mean found in Africa (45%) [10].…”

Section: Introductionmentioning

confidence: 80%

Prospective association between depressive symptoms and blood-pressure related outcomes in Kosovo

Obas

Kwiatkowski

Bytyci-Katanolli

et al. 2023

PLOS Glob Public Health

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Kosovo has the lowest life expectancy in the Western Balkans, where cardiovascular disease (CVD) accounts for over half of all deaths. Depression also contributes to disability in the country, with a prevalence of moderate to severe symptoms reported as high as 42% in the general population. Although the mechanisms are not yet well understood, evidence suggests that depression is an independent risk factor for CVD. Our study assessed the prospective association between depressive symptoms and blood pressure (BP)-related outcomes among primary healthcare users in Kosovo to understand the role of BP in the relationship between depression and CVD. We included 648 primary healthcare users from the KOSCO study. The presence of depressive symptoms was defined as moderate to very severe depressive symptoms (DASS-21 depressive symptoms score ≥14). Multivariable censored regression models assessed prospective associations between baseline depressive symptoms and changes in systolic and diastolic BP while taking hypertension treatment into consideration. Multivariable logistic regression models assessed prospective associations between baseline depressive symptoms and hypertension diagnosis among normotensive patients (n = 226) as well as uncontrolled hypertension in hypertensive patients (n = 422) at follow-up. Depressive symptoms were associated with attenuated diastolic BP (β = -2.84, 95%-CI -4.64 to -1.05, p = 0.002) over a year of follow-up in our fully adjusted model, although the association with systolic BP (β = -1.98, 95%-CI -5.48 to 1.28, p = 0.23) did not meet statistical significance. We found no statistically significant association of depressive symptoms with hypertension diagnosis among initially normotensive people (OR = 1.68, 95%-CI 0.41 to 6.98, p = 0.48), nor with hypertension control among initially hypertensive people (OR = 0.69, 95%-CI 0.34 to 1.41, p = 0.31). Our findings are not consistent with increased BP as an underlying mechanism between depression and elevated CVD risk and contribute valuable evidence to cardiovascular epidemiology, where the mechanisms between depression, hypertension and CVD are yet to be elucidated.

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A systematic review and meta‐analysis of the mental health symptoms during the Covid‐19 pandemic in Southeast Asia

Cited by 52 publications

References 77 publications

COVID-19 and common mental health symptoms in the early phase of the pandemic: An umbrella review of the evidence

COVID-19 and common mental health symptoms in the early phase of the pandemic: An umbrella review of the evidence

Psychological status of medical staff dedicated to nucleic acid collection in COVID-19 epidemic during closed-loop management: A cross-sectional study

Prospective association between depressive symptoms and blood-pressure related outcomes in Kosovo

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