A systematic review and meta-analysis of risk factors associated with healthcare-associated infections among hospitalized patients in Chinese general hospitals from 2001 to2022

Liu, Xinliang; Long, Yuxi; Greenhalgh, Christine; Steeg, Sarah; Li, Hao; Verma, Arpana; Spencer, Angela

doi:10.1016/j.jhin.2023.02.013

Cited by 16 publications

(11 citation statements)

References 26 publications

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“…However, few participants knew about the correct HH techniques, and the knowledge did not translate into practice. This supports the globally reported know–do gap [ 7 , 30 , 31 , 32 ]. Furthermore, most participants were unaware of the importance of washing their hands with soap and water, even if their hands were visibly soiled.…”

Section: Discussionsupporting

confidence: 90%

“…HH is considered a gold standard to prevent the spread of infections, representing one of the most cost-effective and crucial components of SP [ 17 , 18 ]. The knowledge score for the use of recommended WHO HH techniques (how and when to wash/rub hands) was observed to be at an outstanding level [ 20 , 30 ]. A high score for participant knowledge of hand hygiene could be attributed to the training conducted as part of an interventional study [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

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Knowledge, Attitude, Practice, and Perceived Barriers for the Compliance of Standard Precautions among Medical and Nursing Students in Central India

Sharma

Bachani

2023

IJERPH

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Objectives: The aim of this study was to assess and compare (a) the knowledge, attitude, and practice of standard precautions (SPs), (b) the knowledge of post-exposure management, and (c) the perceived barriers underlying the noncompliance with SPs among future healthcare professionals (HCPs), i.e., students of medical and nursing courses in Central India. Setting and participants: A cross-sectional study was conducted in 2017–2018 among students of a medical and a nursing college using a pretested and modified questionnaire. Data were collected during 23 face-to-face sessions. Responses were scored according to standard guidelines of the Centers for Disease Control and Prevention and WHO, where each correct response was given a score of 1. Results: Among 600 participants, 51% of medical students and 75% of nursing students could not select the correct definition of SPs from the given options. Sixty-five percent of medical students (275/423) and 82% of nursing students (145/177) were unaware of the term post-exposure prophylaxis. Overall, knowledge about personal protective equipment and hazard symbols was poor (<25%). Furthermore, although theoretical knowledge about hand hygiene was good (510/600; 85%), its implementation was poor (<30%). Sixty-four percent of participants believed that the use of hand rub replaced the need for handwashing, even for visibly soiled hands. Some of the participants believed that the use of PPE might offend patients (16%). High workload and poor knowledge were other significant barriers underlying the noncompliance with SPs. Conclusions: A suboptimal translation of participants’ knowledge into practice is evident and signifies the presence of the know–do gap. Poor knowledge and inappropriate presumptions about the use of SPs discourage the practice of SPs. This results in increased healthcare-associated infections, increased treatment costs, and a suppressed social economy. The inclusion of a dedicated curriculum with repeated hands-on and practice-based training on SPs is suggested to minimize this know–do gap among future healthcare workers.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Knowledge, Attitude, Practice, and Perceived Barriers for the Compliance of Standard Precautions among Medical and Nursing Students in Central India

Sharma

Bachani

2023

IJERPH

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“…Patients in intensive care units are considered separately, and we recognize that this may not be the severe course of the infection itself, but simply patients in a severe condition by their baseline status, and the infection only makes its own special contribution to the severity of the condition and, of course, to the efficacy of treatment and prognosis. Respiratory support, catheter-based component of intensive care, extracorporeal methods are found by some authors as separate areas of medical care [51,52].…”

Section: Of 12mentioning

confidence: 99%

Antibiotic Therapy, Antibiotic Resistance, Drug-Induced Pathomorphosis, and Evolutionary Medicine

Palyutin¹,

Хохлов²

2023

Preprint

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The first half of the 20th century was noteworthy for the introduction of a unique group of drugs – antibiotics. It drastically changed concepts of infectious diseases treatment, which for centuries remained a scourge of the human population. With improvement of the antibiotic treatment efficacy, humanity has faced the problem of a dramatic increase in antibiotic resistance in bacteria. The COVID-19 pandemic has only exacerbated the problem and posed a new challenge to the medical community in finding solutions, both clinical and organizational and methodological, to fight antibiotic resistance widespread all over the globe. This publication covers some aspects of evolutionary processes in either pathogens or diseases, including ethical perspective.

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“…Hospital-acquired infections (HAI) are a leading cause of morbidity and mortality globally 1 and are mainly attributable to central-line–associated bloodstream infections (CLABSIs), catheter-associated urinary tract infections (CAUTIs), ventilator-associated pneumonia (VAP), and surgical site infections (SSIs). 2 Hospital-acquired infections are acquired by patients after 48 hours of admission to a hospital 3 and were neither present nor incubating at the time of admission.…”

Section: Introductionmentioning

confidence: 99%

“… 2 Hospital-acquired infections are acquired by patients after 48 hours of admission to a hospital 3 and were neither present nor incubating at the time of admission. 1 , 2 Hospital-acquired infections develop in approximately 1 in 31 hospital patients 4 with the intensive care units contributing 9–20% of these infections. 5 …”

Section: Introductionmentioning

confidence: 99%

The burden of hospital-acquired infections (HAI) in sub-Saharan Africa: a systematic review and meta-analysis

Melariri,

Freercks,

van der Merwe

et al. 2024

eClinicalMedicine

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A systematic review and meta-analysis of risk factors associated with healthcare-associated infections among hospitalized patients in Chinese general hospitals from 2001 to2022

Cited by 16 publications

References 26 publications

Knowledge, Attitude, Practice, and Perceived Barriers for the Compliance of Standard Precautions among Medical and Nursing Students in Central India

Knowledge, Attitude, Practice, and Perceived Barriers for the Compliance of Standard Precautions among Medical and Nursing Students in Central India

Antibiotic Therapy, Antibiotic Resistance, Drug-Induced Pathomorphosis, and Evolutionary Medicine

The burden of hospital-acquired infections (HAI) in sub-Saharan Africa: a systematic review and meta-analysis

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