2020
DOI: 10.1051/e3sconf/202021803039
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A systematic review: breast cancer susceptibility genes

Abstract: Breast cancer is the dominant female cancer and the top cause of cancer deaths in women among the world. The susceptible genes are critical risk factors for both hereditary and sporadic breast cancers. The incidence of carcinoma for carriers with mutated relative genes might increase in comparison with that of the normal population. These genes might be applied in breast cancer populated screening and clinical treatment, in order to improve survival of the breast cancer patients. This study concluded some gene… Show more

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Cited by 2 publications
(5 citation statements)
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“…The total monomorphic bands in the breast cancer patient of ABCG2, ER-α, miRNA -152 genes were (12,16,8) bands, while in control were (16,0,12) bands, whereas the monomorphic band may be referred to homogenous genomic regions of the PCR-RAPD-PCR profile.…”
Section: Discussionmentioning
confidence: 92%
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“…The total monomorphic bands in the breast cancer patient of ABCG2, ER-α, miRNA -152 genes were (12,16,8) bands, while in control were (16,0,12) bands, whereas the monomorphic band may be referred to homogenous genomic regions of the PCR-RAPD-PCR profile.…”
Section: Discussionmentioning
confidence: 92%
“…The total polymorphic bands in the BC patient of AB-CG2,ER-α ,mi-RNA 152 genes were (15,18,8 ) respectively, while in control were (14,34,0) bands; The total monomorphic bands in ABCG2,ER-α ,mi-RNA 152 genes of the patients were (12,16,8 ) respectively; while in control were (16, 0, 12) bands; The total unique bands in ABCG2, ER-α, mi-RNA 152 genes were (10, 5, 2) bands in a patient; while in control were (6, 7, 0) bands, as shown in figure (3) and table (3,4,5,6,7,8,9,10,11).…”
Section: Detection Genetic Polymorphism Of Breast Cancer-related Genesmentioning
confidence: 99%
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“…The reaction mixture (20 µL) consisted of template PCR product 2.5 µl, 2.5 µL (OPAA11, OPU15, OPAA17, OPD18) RAPD primer, 7.5µl Nuclease free water, and 7.5 µl GO Taq ®G2 Green master mix. The mixture was incubated in the TECHNE prime thermal cycler (with heating lid) programmed for (35)(36)(37)(38)(39)(40) cycles, each one consisting of as following: a denaturation step (1 min at 94 •C), one annealing step (30 sec at gradient 36-39 •C) and an extension step (1 min at 72 •C).…”
Section: Column Puri Cationmentioning
confidence: 99%
“…Many genes are found related to breast cancer (Sun et al, 2017). The susceptible genes are critical risk factors for both hereditary and sporadic breast cancer (Xie., 2020). ABCB1 gene is located on chromosome 7q21.12 (Sheng X et al, 2012;MUTLU İÇDUYGU et al, 2020).…”
Section: Introductionmentioning
confidence: 99%