A systematic review of 1143 parapharyngeal space tumors reported over 20years

Riffat, Faruque; Dwivedi, Raghav C.; Palme, Carsten E.; Fish, Brian; Jani, Piyush

doi:10.1016/j.oraloncology.2014.02.007

Cited by 191 publications

(250 citation statements)

References 26 publications

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“…We found the recidivation of malignant tumors was significantly higher than benign tumors, and malignant ones always had a worse prognosis. These findings were in accordance with those of other studies (4,6).…”

Section: Discussionsupporting

confidence: 94%

“…By reason of the complexity of LSB surgeries, the postoperative complications are not rare. Hence, there is a risk of intricate problems occurring when care is not taken to reduce damage to the neurovascular structures as much as possible, and a good hemostasis intraoperatively is not achieved, also taking into consideration the corresponding postoperative treatments (4,27).…”

Section: Discussionmentioning

confidence: 99%

“…Most LSBTs are benign (65-75%), and they usually originate from the salivary glands comprising 40-50% of the total. The rest are neurogenic (20%) or otherwise (20%) (3)(4)(5)(6)(7). Manifestations of LSBTs include a mass in the oropharynx or the upper neck, changes in voice, cranial nerve deficits, and so forth.…”

Section: Introductionmentioning

confidence: 99%

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Surgical management and follow-up of lateral skull base tumors: An 8-year review

Kong

Yang

Wang

et al. 2017

Molecular and Clinical Oncology

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Abstract. The purpose of the present article was to describe the diagnostic evaluation of, and surgical approaches to, lateral skull base tumors (LSBTs). The study is a retrospective review of 21 patients diagnosed with tumors that involve lateral skull base (8 with malignant diseases and 13 with benign lesions) who were surgically treated during a 8-year period. The transparotid-transmandibular (38%) was the most commonly performed surgical procedure, followed by the transmandibular (24%), the transmaxillary (24%), the transcervical approach (10%) and the combined approach (4%). The surgical procedures were uneventful and there were no postoperative mortalities. Complications were encountered in 12 cases, and morbidity was not remarkable during the perioperative stages. After an average follow-up of 46 months, only 1 of 14 patients with benign diseases had a recurrence following the resection of a pleomorphic adenoma. Of 7 patients with malignant tumors, 5 are alive with no evidence of disease. The majority of the benign lateral skull base tumors can be removed surgically with a low rate of complications and recurrence. However, malignant neoplasms carry a poor prognosis and a low rate of disease-free survival.

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Section: Discussionsupporting

confidence: 94%

Section: Discussionmentioning

confidence: 99%

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Surgical management and follow-up of lateral skull base tumors: An 8-year review

Kong

Yang

Wang

et al. 2017

Molecular and Clinical Oncology

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“…In a multicentric meta-analysis of 1143 parapharyngeal space tumors presented in 17 studies, Riffat et al showed that the most prestyloid tumors arise from the salivary glands, with a total of 15 different histological types reported in the cumulative series [10].…”

Section: Discussionmentioning

confidence: 99%

Role of 18F-FDG PET Scan in Parapharyngeal Space Tumors: Report of a Rare Case and Review of the Literature

Oa¹,

Biyi²,

En-Nouali³

et al. 2017

J Cancer Sci Ther

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BackgroundParapharyngeal space (PPS) tumors are rare, accounting for 0.5% of all neoplasms of head and neck. PPS tumors may be primary, metastatic or a direct extension of tumors from the adjacent spaces. The frequency of benign and malignant tumors is about 80% and 20%, respectively. Most of them originate from the salivary gland (40-50%), followed by a neurogenic etiology and the remainder are a broad spectrum of miscellaneous tumors [1][2][3][4][5][6][7].The PPS is a lateral pharyngeal region. It is divided by muscular aponeurotic partition into an anterior (prestyloid) muscular compartment and a posterior (poststyloid) neurovascular compartment [1,[3][4][5][6][7]. Imaging is crucial for the assessment of PPS tumors. Surgery is performed based on information provided by these diagnostic modalities.This article will present a case of left parapharyngeal squamos cell carcinoma with unusual spinal metastases, and the potential role of FDG PET/CT will be illustrated. Case PresentationA 36-year-old male patient who showed up in April 2016 with 3 months' history of left side facial paralysis, left trismus, difficulty in swallowing and otological symptoms: otorrhea and otorrhagia. For the last month, he had developed a pharyngeal cavity mass. CT scan head and neck showed well defined heterogeneously enhancing left parapharyngeal solid mass (32×50×62 mm) with multiple area of necrosis, bulging into nasopharynx with extension to pharyngeal mucosal surface.The mass overwhelms the tympanic cavity and spreads to the ipsilateral external auditory meatus and pterygoid muscle. It causes the AbstractBackground: Tumors of the parapharyngeal space (PPS) are rare and account for only 0.5% of head and neck neoplasms. Approximately 80% of these tumors are benign lesions, yet they represent a formidable diagnostic and treatment challenge. They are difficult to diagnose because they have few symptoms, therefore, CT and MRI are essential to delineate the tumor extent, intracranial involvement and relationship to the adjacent vital structures.

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“…Meanwhile, prestyloid tumours mostly develop from salivary gland. It is useful to determine whether tumour is in either pre-or poststyloid compartment, as knowledge of this is helpful in determining possible diagnosis (Table 2) [4].…”

Section: Discussionmentioning

confidence: 99%

Prieryklinio tarpo navikų diagnostikos ypatybės ir sunkumai

Senkus¹,

Gibavičienė²,

Čepulis³

2016

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ĮžangaPrieryklinio tarpo navikai, dažniausiai nepiktybiniai, sudaro apie 0,5 % galvos ir kaklo srities navikų. Jie yra reti, todėl daugelis gydytojų per savo praktiką su šia patologija susiduria nedažnai. Svarbu išskirti kelis prieryklinio tarpo navikų diagnostikos ypatumus: simptomai yra įvairūs ir nespecifiški, o objektyvūs požymiai pasireiškia, kai navikas yra vėlesnės stadijos.Medžiaga ir metodaiŠiame straipsnyje apibendrinami retrospektyviosios šešių prieryklinio tarpo navikų atvejų analizės diagnostiniai aspektai. Visi aptariami pacientai buvo gydyti Nacionaliniame vėžio institute nuo 2004 iki 2016 metų. Straipsnyje apžvelgiame mokslinę literatūrą ir nagrinėjame diagnostikos seką, atkreipdami dėmesį į prieryklinio tarpo navikų diagnozavimo ypatumus bei sunkumus.RezultataiBuvo diagnozuoti trys gerybiniai ir trys piktybiniai navikai. Pacientai skundėsi įvairiais, daugiausia nespecifiniais, simptomais.Daugumai pacientų buvo atlikta priešoperacinė aspiracinė biopsija plona adata, visiems – priešoperacinis radiologinis tyrimas (kompiuterinė tomografija ir (ar) magnetinio rezonanso tomografija.IšvadosVisi gydytojai, susiduriantys su šia patologija, turėtų atkreipti dėmesį, kad prieryklinio tarpo navikų simptomai dažniausiai būna nespecifiniai, o objektyvūs požymiai pasireiškia navikui jau pažengus. Kalbant apie diagnostikos seką, aspiracinė biopsija plona adata yra būtinas tyrimas, siekiant išvengti histologinių netikėtumų. Radiologinis tyrimas, ypač magnetinio rezonanso tomografija, yra naudingas vertinant naviko kilmę, dydį, iš dalies ir tipą.

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A systematic review of 1143 parapharyngeal space tumors reported over 20years

Cited by 191 publications

References 26 publications

Surgical management and follow-up of lateral skull base tumors: An 8-year review

Surgical management and follow-up of lateral skull base tumors: An 8-year review

Role of 18F-FDG PET Scan in Parapharyngeal Space Tumors: Report of a Rare Case and Review of the Literature

Prieryklinio tarpo navikų diagnostikos ypatybės ir sunkumai

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