A systematic review of economic evaluations of public health interventions targeting alcohol, tobacco, illicit drug use and problematic gambling: Using a case study to assess transferability

Nystrand, Camilla; Gebreslassie, Mihretab; Ssegonja, Richard; Feldman, Inna; Sampaio, Filipa

doi:10.1016/j.healthpol.2020.09.002

Cited by 12 publications

(10 citation statements)

References 70 publications

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“…The eligible twenty-two articles referred to HTA transferability in their approach, method, or proposed tool (Supplementary Material S5). Eight articles described their experience of conducting an HTA transfer using a tool (23)(24)(25)(26)(27)(28)(29)(30), twelve articles described transferability tools (4;18-21;31-37), and two articles provided an overview of tools aiding transferability (22;38). No additional tools were identified by the INAHTA questionnaire (seven respondents) or among the conference abstracts (Supplementary Material S3).…”

Section: Resultsmentioning

confidence: 99%

“…Thirdly, country guidelines or reference cases (e.g., SBU checklist (47)) could help to match existing HTAs to local requirements and needs. Likewise, disease-specific reference cases may aid transfers (25). Fourthly, local data can replace parameters in transferred models or HTAs.…”

Section: Discussionmentioning

confidence: 99%

“…The guidance for the steps following these assessments, for instance, on how to interpret added uncertainties of transferability, is limited (steps 4–6). Nor is there a clear consensus on when to use which tools to assess transferability (25;38;52). Most of the identified tools were checklists relevant for economic evaluations, while only a limited number of tools were suitable for systematic reviews that assessed the clinical effectiveness and safety of health interventions.…”

Section: Discussionmentioning

confidence: 99%

“…Checklists were primarily used to assess if results could be adopted (referring to a direct transfer without any changes) in the local setting. Only the article by Nystrand et al (25) used the "Van Mastrigt" guidance (18)(19)(20). They used multiple tools for the transferability assessments, including a country-specific checklist from the Swedish HTA Agency (SBU) that covered transferability items other checklists did not consider (e.g., the feasibility of implementation, standard practice in the comparator, and health financing mechanism) (47).…”

Section: Transfer Approach Guides Interpretation Of Transferability I...mentioning

confidence: 99%

“…The articles included in this mapping all reported on factors and issues that may affect the transferability of HTAs. For instance, it is essential to identify and access relevant HTAs, research papers, or models to avoid duplication (20;23;25;28;29;38). Differences in the context of the technology under review (i.e., resources available, the standard of care, type of health system, and population) further hinder the transferability of HTAs (30;34;37).…”

Section: Hta Transferability Issues To Considermentioning

confidence: 99%

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Considerations for transferability of health technology assessments: a scoping review of tools, methods, and practices

Heupink

Peacocke

Sæterdal

et al. 2022

Int J Technol Assess Health Care

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Health technology assessment (HTA) is commonly used to guide evidence-informed decisions to optimize resource use, prioritize policies, and support countries to achieve universal health coverage. Producing HTAs requires time, scientific expertise, and political commitment, but these are not available in all settings – especially in low- and middle-income countries (LMIC) where HTA processes may be less institutionalized. Transferring and adapting existing HTAs to local settings may offer a solution while reducing duplication efforts. This scoping review aims to provide an overview of tools, methods, approaches, and considerations which can aid HTA transfers. We systematically searched (from 2005 to 2020) six databases and, using predefined inclusion criteria, included twenty-two studies. Data extraction followed a structured process, while synthesis was more iterative. We identified a common approach for HTA transfers. It follows the de novo process of undertaking original HTAs, but with additional steps to assess relevance (applicability), quality, and transferability, as well as steps to adapt parameters where necessary. The EUnetHTA Adaptation Toolkit was the only tool that provided guidance for adapting multiple HTA domains. Other tools were specific to systematic reviews (n = 1) or economic evaluations (n = 12), where one provided guidance for systematic reviews of economic evaluations. Eight papers reported transferring an HTA, with only one transferring to an LMIC. Finally, we reported issues that may facilitate or hinder transferability. In conclusion, we identified fourteen transfer approaches in the form of guidance or checklists, but harmonized and pragmatic guidance for HTA transfers to suit settings with limited HTA capacity seems warranted.

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