A Systematic Review of Ileal Conduit and Neobladder Outcomes in Primary Bladder Cancer

Crozier, Jack; Hennessey, Derek; Sengupta, Shamik; Bolton, Damien; Lawrentschuk, Nathan

doi:10.1016/j.urology.2016.06.034

Cited by 29 publications

(17 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various types of urinary diversions exist and can be either continent (orthotopic neobladder, continent cutaneous reservoir) or incontinent (ileal conduit, ureterocutaneostomy). Incontinent diversions are generally selected for older, sicker patients with advanced disease, whilst continent diversions are created for younger patients with longer life expectancies . While some studies have shown a slight quality of life advantage for continent diversion, this has not been consistent across all studies .…”

Section: Introductionmentioning

confidence: 99%

Hospitalisation and readmission costs after radical cystectomy in a nationally representative sample: does urinary reconstruction matter?

et al. 2018

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Hospitalisation and readmission costs after radical cystectomy in a nationally representative sample: does urinary reconstruction matter?

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Orthotopic neobladder reconstruction is now the preferred option for urinary diversion after radical cystectomy for bladder cancer [ 1 ]. Despite the complexity in surgical procedure and postoperative management, patients with orthotopic neobladder void via native urethra and showed better quality of life compared to patients with incontinent urinary diversion [ 2 ]. Orthotopic neobladder provides low pressure reservoir with adequate capacity preserving urinary continence and upper urinary tract function.…”

Section: Introductionmentioning

confidence: 99%

Cluster analysis identifies three urodynamic patterns in patients with orthotopic neobladder reconstruction

et al. 2017

View full text Add to dashboard Cite

PurposeTo classify patients with orthotopic neobladder based on urodynamic parameters using cluster analysis and to characterize the voiding function of each group.Materials and methodsFrom January 2012 to November 2015, 142 patients with bladder cancer underwent radical cystectomy and Studer neobladder reconstruction at our institute. Of the 142 patients, 103 with complete urodynamic data and information on urinary functional outcomes were included in this study. K-means clustering was performed with urodynamic parameters which included maximal cystometric capacity, residual volume, maximal flow rate, compliance, and detrusor pressure at maximum flow rate. Three groups emerged by cluster analysis. Urodynamic parameters and urinary function outcomes were compared between three groups.ResultsGroup 1 (n = 44) had ideal urodynamic parameters with a mean maximal bladder capacity of 513.3 ml and mean residual urine volume of 33.1 ml. Group 2 (n = 42) was characterized by small bladder capacity with low compliance. Patients in group 2 had higher rates of daytime incontinence and nighttime incontinence than patients in group 1. Group 3 (n = 17) was characterized by large residual urine volume with high compliance. When we examined gender differences in urodynamics and functional outcomes, residual urine volume and the rate of daytime incontinence were only marginally significant. However, females were significantly more likely to belong to group 2 or 3 (P = 0.003). In multivariate analysis to identify factors associated with group 1 which has the most ideal urodynamic pattern, age (OR 0.95, P = 0.017) and male gender (OR 7.57, P = 0.003) were identified as significant factors.ConclusionsWhile patients with ileal neobladder present with various voiding symptoms, three urodynamic patterns were identified by cluster analysis. Approximately half of patients had ideal urodynamic parameters. The other two groups were characterized by large residual urine and small capacity bladder with low compliance. Young age and male gender appear to have a favorable impact on urodynamic and voiding outcomes in patients undergoing orthotopic neobladder reconstruction.

show abstract

“…Orthotopic neobladder was initially preferred by men for the ability to resume a normal method of voiding, without ostomy appliances and the need for pouch catheterization. 7,8 Despite studies by Stenzl et al 9 and Stein et al 2 proving the oncologic safety of female neobladder, it remains underutilized. 1,3 Although few people are performing continent diversions, multiple studies have also shown that even on multivariate analysis women are less likely to receive continent urinary diversion.…”

Section: Discussionmentioning

confidence: 99%

Formal sacrocolpopexy reduces hypercontinence rates in female neobladder formation

Stearns¹,

Donahue

Fathollahi

et al. 2018

Neurourology and Urodynamics

View full text Add to dashboard Cite

show abstract

A Systematic Review of Ileal Conduit and Neobladder Outcomes in Primary Bladder Cancer

Cited by 29 publications

References 27 publications

Hospitalisation and readmission costs after radical cystectomy in a nationally representative sample: does urinary reconstruction matter?

Hospitalisation and readmission costs after radical cystectomy in a nationally representative sample: does urinary reconstruction matter?

Cluster analysis identifies three urodynamic patterns in patients with orthotopic neobladder reconstruction

Formal sacrocolpopexy reduces hypercontinence rates in female neobladder formation

Contact Info

Product

Resources

About