2018
DOI: 10.1371/journal.pone.0191211
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A systematic review of regulatory and educational interventions to reduce the burden associated with the prescriptions of sedative-hypnotics in adults treated for sleep disorders

Abstract: BackgroundThe burden of Sedative-Hypnotics (SHs) has been known since the 1980s. Yet, their consumption remains high. A systematic review of the literature should help to assess efficient interventions to improve the appropriate use of SHs in sleep disorders.ObjectivesTo identify and assess regulatory and educational interventions designed to improve the appropriate use of SHs for insomnia treatment.MethodsWe conducted a systematic review of the literature according to PRISMA guidelines. A systematic search co… Show more

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Cited by 12 publications
(11 citation statements)
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“…The PIMs most commonly used by older drivers are benzodiazepines, nonbenzodiazepine hypnotics, antidepressants, and first-generation antihistamines, all of which have been linked to driving impairment and increased crash risk. Implementation of evidence-based interventions, such as computer-based alerts and prescription rule restrictions [38], may reduce PIM use and improve health outcomes and driving safety in older adults.…”
Section: Resultsmentioning
confidence: 99%
“…The PIMs most commonly used by older drivers are benzodiazepines, nonbenzodiazepine hypnotics, antidepressants, and first-generation antihistamines, all of which have been linked to driving impairment and increased crash risk. Implementation of evidence-based interventions, such as computer-based alerts and prescription rule restrictions [38], may reduce PIM use and improve health outcomes and driving safety in older adults.…”
Section: Resultsmentioning
confidence: 99%
“…Quantitative studies were assessed using the Quality Assessment Tool for quantitative studies developed by the Effective Public Health Practice Project, see Table 3 for an overview of the components of this tool [12]. This tool had been used in another systematic review focused on interventions [13]. Qualitative studies were assessed, using the Critical Appraisal Skills Programme (CASP) Qualitative Research Checklist [14], the main components focused on assessing the methodological limitations, coherence, adequacy of data and relevance of research.…”
Section: Risk Of Biasmentioning
confidence: 99%
“…For instance, insomnia patients with GABA in the occipital cortex has been reported to be consistent with the hyperarousal model of insomnia. In addition, emotional and cognitive systems lead to suppression of sleep-promoting regions such as the ventrolateral preoptic area (VLPO) ( Wang and Liu, 2016 ; Bourcier et al ., 2018 ). In addition, orexin/hypocretin neurons of the lateral hypothalamus project to all of the sleep/insomnia arousal-promoting centers in the brainstem and hypothalamus thereby reinforcing their activity to play on important roles in sleep.…”
Section: An Overview Of Insomniamentioning
confidence: 99%