A systematic review of risk factors for methamphetamine-associated psychosis

Arunogiri, Shalini; Foulds, James; McKetin, Rebecca; Lubman, Dan I.

doi:10.1177/0004867417748750

Cited by 77 publications

(59 citation statements)

References 51 publications

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“…Although a literature review did not find any correlation between sociodemographic characteristics and MAP,11 our study and previous studies did find that male MA users were more likely to experience MAP 27. As two diseases in the same continuum,31 the higher risk of MAP in men appears to be in line with the findings that men are more likely than women to develop schizophrenia 32…”

Section: Discussionsupporting

confidence: 76%

“…In early Japanese studies in which most users exclusively used MA (1955–1992), the investigators found an association between frequent and long-term use of MA and MAP 10. Based on a recent review, replicated risks factors included early-age MA use, frequent and long-term use of MA, MA dependence, alcohol and other drug use, major depressive disorders and antisocial personality disorders 11. That review found no association between sociodemographic factors and MAP.…”

Section: Introductionmentioning

confidence: 99%

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Risks of psychosis in methamphetamine users: cross-sectional study in Thailand

et al. 2019

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ObjectiveTo determine factors related to recent methamphetamine-associated psychosis (MAP) among individuals recently using methamphetamine (MA).DesignCross-sectional study carried out between July 2015 and June 2017.SettingFour mental health hospitals and one substance abuse treatment centre in Thailand.ParticipantsIndividuals recruited onto the study included those aged 18 years or over, of both sexes, who reported MA use in the month prior to admission.MeasuresAny recent psychosis was confirmed using the Mini International Neuropsychiatric Interview-Plus psychotic module. The Timeline Follow Back was used to determine days of MA use. The severity of MA dependence was assessed using the Severity of Dependence Scale. Quantitative hair analysis was carried out to confirm recent use of MA and to measure the amount of MA use. We compared several characteristics between those who had recently experienced psychosis and those who had not.ResultsThis study included 120 participants without MAP and 113 participants with MAP. The mean age was 28 years and the mean abstinence was 17 days. The levels of MA concentration in hair were not significantly different between groups (p=0.115). Based on the final logistic regression model, the independent factors associated with MAP (OR and 95% CI) included being male (OR 4.03, 95% CI 1.59 to 10.20), ≥16 days of MA use in the past month (OR 2.35, 95% CI 1.22 to 4.52), MA dependence (OR 9.41, 95% CI 2.01 to 44.00) and hospitalisation history related to substance abuse (OR 3.85, 95% CI 2.03 to 7.28).ConclusionsHealth professionals should closely monitor the development of MAP in MA-dependent men who frequently use MA and have a history of hospitalisation for substance abuse. The measure of MA concentration levels in the hair may add no benefit for the prediction of the development of MAP.

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Section: Discussionsupporting

confidence: 76%

Section: Introductionmentioning

confidence: 99%

Risks of psychosis in methamphetamine users: cross-sectional study in Thailand

et al. 2019

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“…Furthermore, METH can induce a chronic psychosis in those with no premorbid psychiatric risk factors ( 54 ), suggesting that METH use can induce persistent physiological changes consistent with psychosis that are independent to genetic and personality predispositions. It is recommended that readers examine many of the comprehensive review articles available for further information on the clinical profiles, correlates, and recovery of METH-induced psychosis ( 55 – 60 ). Overall, METH psychosis can result in a persistent psychotic syndrome that is resistant to spontaneous recovery, and in light of the high use of METH use globally, chronic METH psychosis will undoubtedly continue to be an issue for health-care professionals.…”

Section: Chronic Methamphetamine Psychosismentioning

confidence: 99%

A Comparison of Methamphetamine-Induced Psychosis and Schizophrenia: A Review of Positive, Negative, and Cognitive Symptomatology

2018

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Methamphetamine is a potent psychostimulant that can induce psychosis among recreational and chronic users, with some users developing a persistent psychotic syndrome that shows similarities to schizophrenia. This review provides a comprehensive critique of research that has directly compared schizophrenia with acute and chronic METH psychosis, with particular focus on psychiatric and neurocognitive symptomatology. We conclude that while there is considerable overlap in the behavioral and cognitive symptoms between METH psychosis and schizophrenia, there appears to be some evidence that suggests there are divergent aspects to each condition, particularly with acute METH psychosis. Schizophrenia appears to be associated with pronounced thought disorder, negative symptoms more generally and cognitive deficits mediated by the parietal cortex, such as difficulties with selective visual attention, while visual and tactile hallucinations appear to be more prevalent in acute METH-induced psychosis. As such, acute METH psychosis may represent a distinct psychotic disorder to schizophrenia and could be clinically distinguished from a primary psychotic disorder based on the aforementioned behavioral and cognitive sequelae. Preliminary evidence, on the other hand, suggests that chronic METH psychosis may be clinically similar to that of primary psychotic disorders, particularly with respect to positive and cognitive symptomatology, although negative symptoms appear to be more pronounced in schizophrenia. Limitations of the literature and avenues for future research are also discussed.

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“…Strengths of this study included the use of a diagnostic interview (SCID I/P) to exclude pre-existing psychotic disorders, strengthening the interpretation that the symptoms observed in the sample were related to methamphetamine use. This is a key difference in comparison to a substantial number of studies in this area (40). We utilized the Brief Psychiatric Rating Scale (BPRS) (18), a well validated dimensional psychotic symptom measure that has been widely used in other studies of methamphetamine-associated psychosis (19,41) and primary psychotic disorders (42).…”

Section: Discussionmentioning

confidence: 99%

Emotion Recognition and Impulsive Choice in Relation to Methamphetamine Use and Psychosis Symptoms

et al. 2019

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Introduction:The cognitive profiles of people with methamphetamine use disorder are characterized by impulsivity and impairment in social cognition. However, previous studies have not fully accounted for the presence and impact of co-occurring mental health problems on these domains. For instance, psychotic symptoms are commonly experienced by people who use methamphetamine and may influence cognitive performance. We aimed to examine decision making and emotion recognition in individuals with methamphetamine use, compared to healthy controls, to map the nature and degree of impairments in relation to the presence of psychotic symptoms.Method: In this naturalistic study, we assessed reward-based decision-making and facial emotion recognition across three groups, methamphetamine-using individuals with (MAP, n = 29) and without psychotic symptoms (MNP, n = 70), and healthy controls (HC, n = 32). Results:In comparison to healthy controls, methamphetamine-using individuals presented with poorer performance on tasks of decision-making and emotion recognition. Emotion recognition was impaired across all methamphetamine-using individuals, with significantly poorer recognition of anger and sadness in those with psychotic symptoms. Conclusion:We found specific impairments in emotion recognition in relation to psychotic symptoms in people who use methamphetamine regularly. This builds on previous evidence on cognitive profiles in methamphetamine use disorder, highlighting the need to assess co-morbid mental health and psychotic symptoms. Our finding that methamphetamine-using individuals with psychotic symptoms present with particular difficulties recognizing anger has implications for frontline clinicians.

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A systematic review of risk factors for methamphetamine-associated psychosis

Abstract: The most consistent correlates of psychotic symptoms were increased frequency of methamphetamine use and dependence on methamphetamine. The findings of this review highlight the need for targeted assessment and treatment of methamphetamine use in individuals presenting with psychosis.

Cited by 77 publications

References 51 publications

Risks of psychosis in methamphetamine users: cross-sectional study in Thailand

Risks of psychosis in methamphetamine users: cross-sectional study in Thailand

A Comparison of Methamphetamine-Induced Psychosis and Schizophrenia: A Review of Positive, Negative, and Cognitive Symptomatology

Emotion Recognition and Impulsive Choice in Relation to Methamphetamine Use and Psychosis Symptoms

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