2019
DOI: 10.33590/emjurol/10314467
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A Systematic Review of Scrotal Squamous Cell Carcinoma

Abstract: The epidemiology of scrotal cancer has changed over time away from occupational exposure to soot. The current incidence of scrotal malignancy is approximately 1 per 1 million males per year. This review summarises the current literature on the management of scrotal squamous cell carcinoma (SCC), including pathogenesis, available diagnostic tools, current treatment, and overall management strategies. The rarity of SSC cases makes it difficult to recruit patients for studies of this disease. To date, very few s… Show more

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Cited by 2 publications
(7 citation statements)
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“…Scrotal and perineal squamous cell carcinoma (SCC) is a rare, aggressive skin cancer typically seen in older men. 1,2 Risk factors include chronic skin irritation or inflammation, ultraviolet radiation exposure, smoking, human papilloma virus (HPV) infection, and a history of precancerous or cancerous skin lesions. 1,2 Diagnosis is made by biopsy, while imaging modalities such as CT or MRIs can determine cancer's extent.…”
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confidence: 99%
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“…Scrotal and perineal squamous cell carcinoma (SCC) is a rare, aggressive skin cancer typically seen in older men. 1,2 Risk factors include chronic skin irritation or inflammation, ultraviolet radiation exposure, smoking, human papilloma virus (HPV) infection, and a history of precancerous or cancerous skin lesions. 1,2 Diagnosis is made by biopsy, while imaging modalities such as CT or MRIs can determine cancer's extent.…”
mentioning
confidence: 99%
“…1,2 Risk factors include chronic skin irritation or inflammation, ultraviolet radiation exposure, smoking, human papilloma virus (HPV) infection, and a history of precancerous or cancerous skin lesions. 1,2 Diagnosis is made by biopsy, while imaging modalities such as CT or MRIs can determine cancer's extent. 1 Treatment depends on the cancer stage and patient health, with surgery being the mainstay.…”
mentioning
confidence: 99%
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