A systematic review of sleep disorders in patients with chronic kidney disease undergoing hemodialysis

Abstract

The purpose of this study was to conduct a systematic review of the available evidence on sleep disorders in patients with end stage renal disease (ESRD) undergoing hemodialysis (HD). [Subjects and Methods] Two independent reviewers performed a computer-assisted search of the MEDLINE, SciELO, LILACS, and BIREME Virtual Health Library medical databases from their inception to November 2015. [Results] One thousand one hundred twenty-six articles were found that met the inclusion criteria. Articles were excluded if they were not in English, the patients did not undergo HD, or the studies were not cross-sectional or clinical trials. After reading the full text, a further 300 studies were excluded because they did not use polysomnography. The remaining 18 studies with ESRD patients undergoing HD comprised 8 clinical trials and 10 cross-sectional studies. This systematic review followed the criteria outlined by the PRISMA declaration. [Conclusion] In this systematic review, a high prevalence of sleep disorders was observed in ESRD, including sleep-disordered breathing. This knowledge may enable health professionals to devise new strategies for the diagnosis and treatment of these patients, in order to reduce morbidity and mortality and improve their quality of life.

Differential effects of age on quality of sleep and depression in patients receiving maintenance haemodialysis

“…In addition, full polysomnography remains the gold standard for the assessment of sleep disorders in haemodialysis patients. 29 Use of the questionnaire to assess quality of sleep is an alternative that is less costly but should be highlighted. Fourth, one may argue that the subjects might feel embarrassed to honestly answer many private questions in the Questionnaires to the nurses whom they were very acquainted with because they regularly saw each other.…”

Physical Activity and Sleep Patterns in Hemodialysis Patients in a Suburban Environment

“…A systematic review by Fonesca et al [12] found that 50-80% of HD patients suffered from sleep-disordered breathing. There is also a high rate of periodic limb movement disorder and restless leg syndrome.…”

Perfil do sono de pacientes idosos submetidos à hemodiálise

“…Revisão sistemática recente aponta alta prevalência de transtornos do sono em pacientes com DRCT sob hemodiálise intermitente. 16 Estudo realizado por Bastos et al com 100 pacientes submetidos a hemodiálise intermitente identificou má qualidade do sono em 75% deles (Pittsburgh Sleep Quality Index ≥ 6). 17 Na mesma direção, estudos têm demonstrado sonolência diurna excessiva em pacientes 5 durante as sessões de hemodiálise.…”