A systematic review of studies investigating the care of stroke survivors in long-term care facilities

Teo, Keith; Slark, Julia

doi:10.3109/09638288.2015.1059496

Cited by 20 publications

(27 citation statements)

References 52 publications

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“…The findings suggest that, in Ireland, nearly one in five nursing home residents have experienced stroke prior to admission. Given that the national and international estimates of the prevalence of stroke among nursing home residents include stroke cases both before and after nursing home admission, the estimate of 17% (95% CI = 14.3–20.2%; N = 111) found in this study appears to be consistent with that found in the international literature (18–25%) [ 20 , 21 , 42 , 43 , 44 ].…”

Section: Discussionsupporting

confidence: 87%

“…Consequently, the strength of the effect of PSCI on nursing home placement has varied between studies [ 16 ]. The characteristics of stroke survivors admitted to nursing homes have been examined in a number of studies [ 17 , 18 , 19 , 20 , 21 ]. These studies found high levels of care needs amongst stroke survivors residing in nursing homes.…”

Section: Introductionmentioning

confidence: 99%

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The Prevalence of Cognitive Impairment on Admission to Nursing Home among Residents with and without Stroke: A Cross–Sectional Survey of Nursing Homes in Ireland

Donnelly

Sexton

Merriman

et al. 2020

IJERPH

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Post–stroke cognitive impairment (PSCI) is a common consequence of stroke. Epidemiological evidence indicates that, with an ageing population, stroke and PSCI are likely to increase in the coming decades. This may have considerable implications for the demand for nursing home placement. As prevalence estimates of both cognitive impairment and dementia on admission to nursing home among residents with and without stroke have not yet been compared, they were estimated and compared in this study. We performed a cross–sectional survey to establish the admission characteristics of 643 residents in 13 randomly selected nursing homes in Ireland. The survey collected data on resident’s stroke and cognitive status at the time of nursing home admission. The survey found, among nursing home residents that experienced stroke prior to admission, prevalence estimates for cognitive impairment (83.8%; 95% CI = 76.9–90.6%) and dementia (66.7%; 95% CI = 57.9–75.4%) were significantly higher compared to residents that had not experienced stroke prior to admission (cognitive impairment: 56.6%; 95% CI = 52.4–60.8%; X2 (1) = 28.64; p < 0.001; dementia: 49.8%; 95% CI = 45.6–54.1%; X2 (1) = 10.47; p < 0.01). Since the prevalence of PSCI is likely to increase in the coming decades, the findings highlight an urgent need for health service planning for this increased demand for nursing home care to meet the care needs of these stroke survivors.

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Section: Discussionsupporting

confidence: 87%

Section: Introductionmentioning

confidence: 99%

The Prevalence of Cognitive Impairment on Admission to Nursing Home among Residents with and without Stroke: A Cross–Sectional Survey of Nursing Homes in Ireland

Donnelly

Sexton

Merriman

et al. 2020

IJERPH

View full text Add to dashboard Cite

show abstract

“…There are approximately 30 million stroke survivors globally, and they comprise approximately one-quarter of the residents in long-term care (LTC) facilities. The care for stroke survivors in LTC facilities is lacking in rehabilitation, stroke-specific care, and secondary stroke prevention [ 43 ]. Additionally, it is necessary to continue in follow-up examinations, which are essential for coordinating post-acute services and monitoring of the patient’s progress [ 44 ].…”

Section: Introductionmentioning

confidence: 99%

B-Type Natriuretic Peptide as a Significant Brain Biomarker for Stroke Triaging Using a Bedside Point-of-Care Monitoring Biosensor

et al. 2020

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Stroke is a widespread condition that causes 7 million deaths globally. Survivors suffer from a range of disabilities that affect their everyday life. It is a complex condition and there is a need to monitor the different signals that are associated with it. Stroke patients need to be rapidly diagnosed in the emergency department in order to allow the admission of the time-limited treatment of tissue plasminogen activator (tPA). Stroke diagnostics show the use of sophisticated technologies; however, they still contain limitations. The hidden information and technological advancements behind the utilization of biomarkers for stroke triaging are significant. Stroke biomarkers can revolutionize the way stroke patients are diagnosed, monitored, and how they recover. Different biomarkers indicate different cascades and exhibit unique expression patterns which are connected to certain pathologies in the human body. Over the past decades, B-type natriuretic peptide (BNP) and its derivative N-terminal fragment (NT-proBNP) have been increasingly investigated and highlighted as significant cardiovascular biomarkers. This work reviews the recent studies that have reported on the usefulness of BNP and NT-proBNP for stroke triaging. Their classification association is also presented, with increased mortality in stroke, correlation with cardioembolic stroke, and an indication of a second stroke recurrence. Moreover, recent scientific efforts conducted for the technological advancement of a bedside point-of-care (POC) device for BNP and NT-proBNP measurements are discussed. The conclusions presented in this review may hopefully assist in the major efforts that are currently being conducted in order to improve the care of stroke patients.

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“…In addition, the main focus of poststroke care is the outcome improvement and prevention of secondary stroke reoccurence; this is conducted using various tests, such as regular NT-proBNP monitoring. [91][92][93] whereby levels greater than 255 pg mL -1 pose significantly higher risk with a sensitivity of 76% and specificity of 60% (44). Today, NT-proBNP level is routinely measured using various immunoassay techniques (94), especially enzyme-linked immunosorbent assay (ELISA) for heart failure diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical impedimetric detection of stroke biomarker NT-proBNP using disposable screen-printed gold electrodes

Sinawang

Harpaz

Fajs

et al. 2017

The EuroBiotech Journal

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Stroke is the second top leading cause of death globally. It is caused by an abrupt interruption of blood flow to the brain. In that course, brain natriuretic peptide (BNP) and its derivative N-terminal pro b-type natriuretic peptide (NT-proBNP), neurohormones produced mainly by the heart ventricles in response to excessive stretching of cardiomyocytes (heart muscle cells), are proven to be good biomarkers for heart failure diagnosis. Moreover, there is growing clinical interest of the use of NT-proBNP for stroke diagnosis and prognosis because it is significantly associated with cardioembolic stroke and secondary stroke reoccurrence, with sensitivity >90% and specificity >80%. However, in diagnostic settings, there is still a need to address the encountered analytical problems, particularly assay specificity and set up. In this study, a novel approach for NT-proBNP detection is demonstrated using an electrochemical immunoassay method. A label-free impedimetry immunosensor for stroke biomarker was developed using modified disposable screen-printed gold electrodes (SPGE) hosting specific anti-NT-proBNP capture antibody. The performance of our immunosensor was studied in the presence of NT-proBNP in both buffered and mock (porcine) plasma samples. A linear relation between the relative total resistance (ΔRtot) responses and the NT-proBNP concentrations in buffer was observed in a range from 0.1 to 5 ng mL-1 with a correlation coefficient (R2) of 0.94656. Overall, the biosensor has demonstrated the capability to quantitate NT-proBNP and differentiate such concentrations in a low concentration range, especially among 0, 0.1, 0.5, 1, and 3 ng mL-1 in plasma samples within 25 min. This range is valuable not only for classifying cardioembolic stroke (higher or equal to 0.5 ng mL-1), but also predicting the risk of secondary stroke reoccurrence (higher than 0.255 ng mL-1). Our biosensor has the potential to be used as an easy-to-use point-of-care test that is both accurate and affordable.

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A systematic review of studies investigating the care of stroke survivors in long-term care facilities

Cited by 20 publications

References 52 publications

The Prevalence of Cognitive Impairment on Admission to Nursing Home among Residents with and without Stroke: A Cross–Sectional Survey of Nursing Homes in Ireland

The Prevalence of Cognitive Impairment on Admission to Nursing Home among Residents with and without Stroke: A Cross–Sectional Survey of Nursing Homes in Ireland

B-Type Natriuretic Peptide as a Significant Brain Biomarker for Stroke Triaging Using a Bedside Point-of-Care Monitoring Biosensor

Electrochemical impedimetric detection of stroke biomarker NT-proBNP using disposable screen-printed gold electrodes

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