A systematic review protocol of Tuina for children with acute bronchitis

Feng, Huichao; Rong, Jian; Pei, Ke; Jing, Fushi; Zhuang, Qian; Lu, Tianjiao; Jing, Fujie; Yang, Jiguo

doi:10.1097/md.0000000000018899

Cited by 6 publications

(3 citation statements)

References 16 publications

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“…Tuina (Chinese Massage), based on the viscera theory, meridian theory, 5 elements theory, is a kind of physical therapy of traditional Chinese medicine with a long history. [14] Many Tuina therapy for PD have been reported: spinal Tuina, [15] viscera Tuina [16] aromatherapy massage, [17] rhythmical massage therapy. [18] Acupressure therapy is also used to treat PD, such as pressing Sanyinjiao (SP6), [19] pressing Taichong (LR3).…”

Section: Description and Function Of Interventionmentioning

confidence: 99%

A systematic review of Tuina for women with primary dysmenorrhea

Lv¹,

Feng²,

Jing

et al. 2021

Medicine

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Background: Primary dysmenorrhea (PD) occurs most often in adolescent girls. Tuina, a kind of Chinese massage, can effectively relieve women's pain and is widely used in clinical practice. However, there is no relevant systematic review show its effectiveness and safety. The study aims to assess the effectiveness and safety of Tuina for PD. Methods:The following electronic databases will be searched from the respective dates of database inception to September 1st,

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Section: Description and Function Of Interventionmentioning

confidence: 99%

A systematic review of Tuina for women with primary dysmenorrhea

Lv¹,

Feng²,

Jing

et al. 2021

Medicine

Self Cite

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“…Tuina, a massage remedy built on Chinese Medicine meridian theories and Zang-Fu organs, consolidates contemporary scientific knowledge, including anatomy, biomechanical role, and physiology. Previous randomized controlled trials (RCTs) have supported the effectiveness of Tuina for the treatment of different health conditions, such as acute bronchitis [ 4 ] and musculoskeletal disorders [ 5 , 6 ]. In relation to KOA, 2 systematic reviews have identified positive clinical effects of Tuina in improving the outcomes of patients with KOA [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Cerebral Mechanism of Tuina on the Descending Pain Inhibitory System in Knee Osteoarthritis: Protocol for a Randomized Controlled Trial

Xu,

Wang,

Wang

et al. 2024

JMIR Res Protoc

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Background Knee osteoarthritis (KOA) is reputedly the most common musculoskeletal disease of the lower limbs and the main cause of pain and disability among older individuals. Pain is the most significant and widespread symptom of KOA. The descending pain inhibitory system has a cardinal role in normal pain consciousness, and its malfunction may be one of the pathophysiological mechanisms in KOA. Crucially, the rostral ventromedial medulla (RVM) and periaqueductal gray (PAG), as important components of the descending pain inhibitory system, directly modulate the activity of the spinal neurons involved in pain transmission. Tuina, a manual therapy, is effective and safe for reducing clinical symptoms of KOA; however, the mechanism that influences pain through the descending pain inhibitory system in KOA is unclear. Objective This study aims to investigate the modulatory implications of Tuina on the RVM and PAG, which have critical roles in the descending pain inhibitory system in patients with KOA. Methods This randomized controlled parallel trial will be conducted at the Tuina Clinic of the Third Affiliated Hospital of Henan University of Chinese Medicine (Zhengzhou, China). Patients with KOA will be randomly assigned (1:1) to 6 weeks of health education or Tuina. All patients in both groups will accept a resting-state functional magnetic resonance scan at the beginning and end of the experiment, and the resting-state functional connectivity and the voxel-based morphometry analysis will be performed to detect the RVM and PAG function and structure changes. The clinical outcome assessments will be (1) the pressure pain thresholds, (2) the Numerical Rating Scale, (3) the Hamilton Depression Scale (HAMD), and (4) the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Considering that this trial is a study of resting-state functional magnetic resonance imaging technology, resting-state functional connectivity and voxel-based morphometry are the primary outcomes, and clinical outcome assessments are secondary outcomes. Adverse events will be documented and assessed throughout. All main analyses will be carried out on the basis of the intention-to-treat principle. The outcome evaluators and data statisticians will be masked to the treatment group assignment to reduce the risk of bias. Results This trial was approved by the ethics committee of the Third Affiliated Hospital of Henan University of Chinese Medicine. Enrollment began in December 2023, and the results of this trial are expected to be submitted for publication in May 2025. Conclusions This trial will identify a possible relationship between function and structure changes of RVM and PAG and the improvement of clinical variables, elucidating the effect of Tuina on the descending pain inhibitory system of patients with KOA. This trial will provide much-needed knowledge for Tuina for patients with KOA. Trial Registration Chinese Clinical Trial Registry ChiCTR2300070289; https://www.chictr.org.cn/showproj.html?proj=182570 International Registered Report Identifier (IRRID) PRR1-10.2196/52820

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“…Previous randomized controlled trials (RCT) have supported the effectiveness of Tuina for the treatment of different health conditions, such as musculoskeletal disorders [9,10] and acute bronchitis [11]. With regard to KOA, two systematic reviews have shown a positive clinical effect of Tuina in improving outcomes for patients with KOA [12,13].…”

Section: Introductionmentioning

confidence: 99%

The cerebral mechanism of Tuina for treating knee osteoarthritis pain: study protocol for a randomized controlled parallel trial

Xiao

Zhao

et al. 2021

Preprint

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Background: Despite the high prevalence and socioeconomic impact of knee osteoarthritis (KOA), treatments for KOA are often unsatisfactory, with wide variation in effectiveness across patients. Tuina is one treatment that is frequently prescribed for patients with KOA. However, how Tuina influences the activity of the central nervous system to alleviate KOA pain remains unclear. Our randomized controlled parallel trial was designed to address this gap through a comparative evaluation of the effect of Tuina on the resting-state functional connectivity (rsFC) of the brain in patients with KOA compared to treatment using celecoxib as the control.Methods/design: This will be a randomized controlled parallel trial to be conducted between June 2022 and June 2024. Forty-eight participants with KOA will be enrolled and randomly allocated to one of two groups, the Tuina treatment group or the celecoxib (control) group. Participants in each of the two groups will undergo 6 weeks treatment. Resting-state functional magnetic resonance imaging (fMRI) will be performed to quantify rsFC at baseline, before treatment, and at the end of the intervention, where rsFC will be used to evaluate the effects of treatment on brain activity. The following self-reported scales will be used as clinical measures of symptomology: the Numerical Rating Scale to quantify the severity of pain, the Pain Catastrophizing Scale to quantify emotional response to pain, and the Hamilton Anxiety Scale and the Hamilton Depression Scale to quantify the cognitive response to pain. Scale scores will be obtained before and after treatment to measure clinical change. Adverse events will be documented and assessed throughout the trial.Discussion: The results of our trial will provide evidence of the effect of Tuina treatment on the rsFC of patients with KOA and identify the possible relationship between a change in the rsFC and improvement of clinical variables, thus elucidating the central mechanism by which Tuina improves pain in KOA.Trial registration: Registered in the Chinese Clinical Trial Registry (http://www.chictr.org.cn/searchproj.aspx, ChiCTR2100045990). Date of registration: 1 May 2021.

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A systematic review protocol of Tuina for children with acute bronchitis

Cited by 6 publications

References 16 publications

A systematic review of Tuina for women with primary dysmenorrhea

A systematic review of Tuina for women with primary dysmenorrhea

Cerebral Mechanism of Tuina on the Descending Pain Inhibitory System in Knee Osteoarthritis: Protocol for a Randomized Controlled Trial

The cerebral mechanism of Tuina for treating knee osteoarthritis pain: study protocol for a randomized controlled parallel trial

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