2018
DOI: 10.1371/journal.pone.0194952
|View full text |Cite
|
Sign up to set email alerts
|

A systematic scoping review on the consequences of stress-related hyperglycaemia

Abstract: BackgroundStress-related hyperglycaemia (SHG) is commonly seen in acutely ill patients and has been associated with poor outcomes in many studies performed in different acute care settings. We aimed to review the available evidence describing the associations between SHG and different outcomes in acutely ill patients admitted to an ICU. Study designs, populations, and outcome measures used in observational studies were analysed.MethodsWe conducted a systematic scoping review of observational studies following … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

2
26
0
2

Year Published

2018
2018
2022
2022

Publication Types

Select...
10

Relationship

1
9

Authors

Journals

citations
Cited by 46 publications
(30 citation statements)
references
References 76 publications
2
26
0
2
Order By: Relevance
“…This suggest that stress hyperglycemia (defined by the American Diabetes Association [6] as a transient elevation in blood glucose in the setting of acute illness or after surgery in a patient with an A1C < 6.5%), may have a worser outcome in acute illness, compared to a previously diagnosed diabetes. This finding is not unexpected, given that the similar worser outcome was observed with stress hyperglycemia in previous meta-analyses [7,8]. Interestingly, stress hypoglycemia was one of the poor prognostic factors and had been associated with a significant increase in respiratory failure and death during the SARS-CoV-1 outbreak in 2003e2004, along with the diabetes [9].…”
Section: Resultssupporting
confidence: 69%
“…This suggest that stress hyperglycemia (defined by the American Diabetes Association [6] as a transient elevation in blood glucose in the setting of acute illness or after surgery in a patient with an A1C < 6.5%), may have a worser outcome in acute illness, compared to a previously diagnosed diabetes. This finding is not unexpected, given that the similar worser outcome was observed with stress hyperglycemia in previous meta-analyses [7,8]. Interestingly, stress hypoglycemia was one of the poor prognostic factors and had been associated with a significant increase in respiratory failure and death during the SARS-CoV-1 outbreak in 2003e2004, along with the diabetes [9].…”
Section: Resultssupporting
confidence: 69%
“…45 Acute (stress) hyperglycemia per se in the setting of severe illness or surgery is associated with longer length of hospital stay, higher infection rates, longer duration of ventilator management, and increased mortality. 47 Stress hyperglycemia occurs in individuals without diabetes and is thought to result from a surge of catecholamines and especially cortisol in response to acute stress. 48 In COVID-19 illness, direct damage of β-cells due to entry of the virus through cell surface ACE2 protein can lead to cell damage and apoptosis causing relative insulin deficiency and acute hyperglycemic state.…”
Section: T2dm Hyperglycemia and Severity Of Covid-19mentioning
confidence: 99%
“…From large epidemiologic studies, BG concentrations are raised in severely ill patients, in different settings including emergency departments [23,24], ICUs [14,25,26], and cardiac care units [27]. Observational studies have documented that hyperglycemia after cardiothoracic surgical procedures is associated with twofold increases of the incidence of wound infection [28,29].…”
Section: Hyperglycemiamentioning
confidence: 99%