A systematic study on ternary inclusion crystals consisting of dianilines and three positional isomers of ditoluoyl-l-tartaric acid

Abstract

The structure and inclusion ability of eight types of salts prepared from a combination of four tartaric acid derivatives (dibenzoyl-and three positional isomers of ditoluoyl-L-tartaric acid) and two V-shaped dianilines were investigated. They afforded 1 : 1 or 2 : 1 stoichiometric salts and the hydrogen-bonding networks changed from three-dimensional to two-and one-dimensional networks as the distance between the methyl and carboxyl groups on the tartaric acid increased. When the methylene group of dianiline was changed to an oxygen atom, the molecular structure became thinner, forming a different hydrogenbonding network. Despite such diverse hydrogen-bonding networks, all the salts incorporated water and/ or 2-butanol molecules in their structure, affording ternary or quaternary inclusion crystals.

Formation of Ternary Inclusion Crystal and Enantioseparation of Alkyl Aryl Sulfoxides by the Salt of Urea-Modified l-Phenylalanine and an Achiral Amine

“…For efficient screening of the host molecules, supramolecular host systems consisting of chiral and achiral components are useful because their components can be easily interchanged without further synthesis of the optically active compound. Such bimolecular hosts afford ternary inclusion crystals by incorporation of guest molecules; however, the design of ternary organic crystals is challenging, as one- or two-component crystals can be favorably crystallized in such processes. − …”