A Systemic Increase in Capillary Permeability in Septicemia

Petrakos, Andrew; Myers, Mary Lee; Holliday, Ronald L.; Finley, Richard; Driedger, Al; Sibbald, William J.

doi:10.1097/00003246-198103000-00282

Cited by 4 publications

(3 citation statements)

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“…In addition to the changes in energy and protein metabolism, there are (in septic and injured patients) profound changes in the metabolism of salt and water and in the volume and composition of body fluid compartments. The presence of sepsis, profound shock, and tissue damage leads to impaired capillary permeability [15][16][17] with resultant obligatory expansion of the interstitial fluid space [18] during treatment of shock.…”

Section: Salt and Water Metabolismmentioning

confidence: 99%

Nutritional support in the management of critically ill patients in surgical intensive care

Streat

Hill

1987

World j. surg.

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Nutritional support is given to many patients in surgical intensive care after major trauma and serious sepsis but rarely after major elective surgery. We have quantified the changes in body composition that occur in these patients and have found that serious losses of body protein still occur after trauma and sepsis despite nutritional support. Correct nutritional management of critically ill patients in surgical intensive care depends on an understanding of the underlying physiology, drainage of sepsis, a high standard of general intensive care measures, and appreciation of sound principles of administration of intravenous nutrition.

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Section: Salt and Water Metabolismmentioning

confidence: 99%

Nutritional support in the management of critically ill patients in surgical intensive care

Streat

Hill

1987

World j. surg.

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“…Any changes in total body protein content in patients receiving nutritional support are likely to be small. Furthermore, septic patients have large changes in the volume of body fluid compartments [20]. The impaired capillary permeability caused by sepsis and pancreatitis leads to an expansion of the interstitial tissue spaces [20].…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, septic patients have large changes in the volume of body fluid compartments [20]. The impaired capillary permeability caused by sepsis and pancreatitis leads to an expansion of the interstitial tissue spaces [20]. This expanding layer of extracellular water may mask the actual loss of muscle mass as it is included in the MUAMC measurement.…”

Section: Discussionmentioning

confidence: 99%