Nearly all theoretical approaches and therapies to criminal thinking and behavior have been reductionist, meaning that they focus on a part or a subsystem of a system or a supra-system. While these reductionist theories and therapies have provided, and continue to provide, valuable information and rehabilitation, they offer a limited view of criminality and rehabilitation as a consequence of reductionism. Using general systems theory (GST), this article presents an integrated and interdisciplinary theoretical approach to criminal thinking and behavior. This article posits that criminality can be better understood, prevented, and treated using GST.