2016
DOI: 10.1104/pp.16.00417
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A Tale of Two Sugars: Trehalose 6-Phosphate and Sucrose

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citations
Cited by 403 publications
(408 citation statements)
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References 172 publications
(318 reference statements)
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“…Despite their common function in promoting growth in response to carbon availability, no direct interaction between T6P and TOR signaling has been identified (Figueroa and Lunn, 2016), which supports the view that T6P is mainly involved in Suc signaling, whereas TOR may be responsible for Glc signaling (Dobrenel et al, 2016), although independently of the HXK1-dependent Glc signaling pathway (Xiong et al, 2013).…”
supporting
confidence: 57%
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“…Despite their common function in promoting growth in response to carbon availability, no direct interaction between T6P and TOR signaling has been identified (Figueroa and Lunn, 2016), which supports the view that T6P is mainly involved in Suc signaling, whereas TOR may be responsible for Glc signaling (Dobrenel et al, 2016), although independently of the HXK1-dependent Glc signaling pathway (Xiong et al, 2013).…”
supporting
confidence: 57%
“…T6P is synthesized from UDP-Glc and Glc-6-P by T6P synthase (TPS) and hydrolyzed to trehalose by T6P phosphatase (TPP). It accumulates under conditions when Suc content is high and has been proposed to act as a signal for Suc availability (Nunes et al, 2013a;Yadav et al, 2014;Figueroa and Lunn, 2016). The role of T6P in regulating sourcesink interactions during plant development is further discussed by O'Hara et al (2013) and Griffiths et al (2016a).…”
mentioning
confidence: 99%
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“…The Suc-T6P nexus model postulates that T6P is both a signal and negative feedback regulator of Suc levels (Lunn et al, 2006;Yadav et al, 2014), regulating the production of Suc in source leaves (Martins et al, 2013; and the utilization of Suc for growth of sink organs (Schluepmann et al, 2003;Zhang et al, 2009). In Arabidopsis and other species, tps and tpp mutants show a diverse range of phenotypic defects, demonstrating that the pathway of trehalose biosynthesis is essential for normal growth and development (for review, see Figueroa and Lunn, 2016). Induced, short-term increases in T6P lead to inhibition of transitory starch breakdown in leaves at night (Martins et al, 2013).…”
Section: Metabolite Controlmentioning
confidence: 99%
“…Se ha propuesto que uno de los factores que afecta al momento de la aparición del GPA son las relaciones entre órganos fuente y órganos sumidero donde existe una removilización de azúcares y aminoácidos que se distribuyen hacia los órganos en desarrollo. La trehalosa-6-fosfato (Tre6P) es un intermediario en la biosíntesis de trehalosa, que además actúa como un metabolito señal importante para la regulación de la síntesis y degradación de azúcares, y está relacionado con KINASE1 (SnRK1) y TARGET DE RAPAMICINA (TOR), a su vez implicados en procesos de senescencia (Figueroa and Lunn, 2016;Thomas, 2013). AP2 podría estar regulando negativamente todos esos genes y así impidiendo el comienzo de la senescencia del SAM.…”
Section: La Sobreexpresión De Ap2 En El Meristemo Apical En Estadiosunclassified