The redshifted 21 cm line is an emerging tool in cosmology, in principle permitting three-dimensional surveys of our Universe that reach unprecedentedly large volumes, previously inaccessible length scales, and hitherto unexplored epochs of our cosmic timeline. Large radio telescopes have been constructed for this purpose, and in recent years there has been considerable progress in transforming 21 cm cosmology from a field of considerable theoretical promise to one of observational reality. Increasingly, practitioners in the field are coming to the realization that the success of observational 21 cm cosmology will hinge on software algorithms and analysis pipelines just as much as it does on careful hardware design and telescope construction. This review provides a pedagogical introduction to stateof-the-art ideas in 21 cm data analysis, covering a wide variety of steps in a typical analysis pipeline, from calibration to foreground subtraction to mapmaking to power spectrum estimation to parameter estimation.∆ 2 (k) [(mK) 2 ] z = 10, x HI = 0.878 z = 9, x HI = 0.776 z = 8, x HI = 0.595 z = 7, x HI = 0.283 z = 6, x HI = 0.004