A Temperature‐Sensing Hydrogel Coating on The Medical Catheter

Abstract

Medical surgical catheters are widely used in the medical field for drug delivery or postoperative drainage. However, infections associated with local temperature rise often occur at the catheter‐tissue interface, resulting in irreversible pathological damage, cognitive behavioral abnormalities, or even an increased risk of mortality if not monitored in time. Herein, an in situ temperature‐sensing hydrogel coating on the outer surface of medical surgical catheters for real‐time infection monitoring is developed. The hydrogel coating exhibits a record temperature coefficient of resistance of 2.90% °C−1 and maintains stable in vivo. Besides, the hydrogel layer forms a mechanically compatible catheter‐tissue interface and minimizes the risk of inflammatory responses due to its tissue‐like softness (Young's modulus of 4.24 kPa). By applying it in the early detection of infections in the brain of SD rats, the individual survival rate has increased to 90% with timely intervention.

Temperature-Tolerant Versatile Conductive Zwitterionic Nanocomposite Organohydrogel toward Multisensory Applications

“…The decreasing electrical resistance with temperature is primarily ascribed to stretching of the two-dimensional rGO nanosheets by the action of polymer chains during the heating process, producing more efficient conductive pathways that facilitate electron transmission. Moreover, the calculated TCR values are −4.2 and −0.04 °C –1 in the range of −40 to 10 °C and 10–60 °C, respectively, which are superior to those of most reported counterparts (Figure S7), ,− manifesting a favorable thermal response performance. Meanwhile, stable temperature sensing behaviors in cyclic testing through switching the temperature from 25 °C to −20, −30, and −40 °C (Figure b) as well as 40, 50, and 60 °C (Figure c) can be detected, proving the satisfactory temperature sensing reliability and replicability of the MSCG-OH.…”

Growth of Double-Network Tough Hydrogel Coatings by Surface-Initiated Polymerization

“…Owing to their lubricating properties in aqueous environments, hydrogels have been utilized as lubricious coatings on diverse substrates. Lubricious hydrogel coatings hold significant potential for applications in the biomedical field, such as coating a metal guidewire or catheter with a lubricious hydrogel. ,, In this study, we assess the frictional properties of the DN hydrogel coating on various substrates under different conditions, including normal loads, contact sizes, coating thicknesses, and sliding speeds. The friction coefficient, defined as the ratio of friction force to normal force, is used to quantify the lubricity performance of the DN hydrogel coating.…”

Strain-Temperature Dual Sensor Based on Deep Learning Strategy for Human–Computer Interaction Systems

“…Recently, due to advances in electronic technology, there has been a significant trend toward smaller, more flexible, and wearable electronic devices. These flexible wearables are highly sensitive, biocompatible, and comfortable and have applications in human medical monitoring, − soft robotics, , electronic skin, , and artificial intelligence. , Current sensor technologies primarily utilize capacitive, , piezoelectric, , resistive, and optical sensing methods. , However, developing a versatile electronic skin using a single sensing material remains a major challenge for widespread adoption …”